Description

Diclofenak natrium (diclofenac) 0.025 g. capsules №30

Ingredients

Active ingredient: Diclofenac sodium 0.025 g per capsule. Other ingredients may include lactose, maize starch, povidone, and magnesium stearate.

Dosage

Dosage: The usual dose is 1 capsule taken 2-3 times a day with food. Do not exceed the recommended dose unless directed by a healthcare provider.

Indications

Indications: Diclofenac is commonly used to relieve pain, inflammation, and swelling caused by various conditions such as arthritis, gout, and sprains.

Contraindications

Contraindications: Avoid this medication if you have a history of allergic reactions to NSAIDs, peptic ulcers, or kidney problems. Consult a doctor before use.

Directions

Directions: Swallow the capsule whole with a full glass of water. Do not crush or chew the capsule. Follow the instructions provided by your healthcare professional.

Scientific Evidence

Diclofenac, the active ingredient in these capsules, has been extensively studied for its efficacy in managing pain and inflammation. Research published in the Journal of Pain Research has shown that diclofenac is effective in reducing pain intensity and improving physical function in patients with osteoarthritis.

Additional Information

It is important to note that diclofenac may increase the risk of serious cardiovascular events, especially when used at high doses or for long periods. Always use the lowest effective dose for the shortest duration necessary to control symptoms.

Pharmacological Effects

Diclofenac works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins which are responsible for pain and inflammation. This action helps to alleviate symptoms associated with various inflammatory conditions.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the effectiveness of diclofenac in providing relief from pain and inflammation comparable to other nonsteroidal anti-inflammatory drugs (NSAIDs). A study published in the Journal of Clinical Rheumatology found diclofenac to be as effective as celecoxib in managing symptoms of osteoarthritis.

Overall, diclofenac natrium capsules are a well-established treatment option for pain and inflammation, supported by scientific evidence and clinical trials. Always consult with a healthcare professional before starting any new medication regimen.