Description

Diclofenak natrium (diclofenac) 2.5% 3 ml. №10

Ingredients

Active ingredient: Diclofenac sodium 2.5%
Other ingredients: Please refer to the product packaging or leaflet for a full list of ingredients.

Dosage

Dosage: Apply a thin layer of the gel to the affected area 3-4 times daily. Do not exceed the recommended dose.

Indications

Indicated for: Relief of pain and inflammation associated with musculoskeletal conditions such as arthritis, sprains, and strains.

Contraindications

Do not use if: You are allergic to diclofenac or other NSAIDs, have a history of asthma attacks, or are in the third trimester of pregnancy.

Directions

Directions for use: Clean and dry the affected area before applying the gel. Gently massage the gel into the skin until fully absorbed. Wash hands after application.

Scientific Evidence

Diclofenak natrium (diclofenac) 2.5% gel has been extensively studied for its efficacy in managing pain and inflammation. Research published in the Journal of Pain Research demonstrated that topical diclofenac formulations provide effective pain relief with minimal systemic side effects.

Additional Information

It is important to follow the recommended dosage and avoid applying the gel to broken or irritated skin. Consult a healthcare professional before using this product, especially if you have a history of gastrointestinal disorders or are taking other medications.

Pharmacological Effects

Diclofenac, the active ingredient in this gel, exerts its pharmacological effects by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins involved in the inflammatory process. This action helps alleviate pain and swelling at the site of application.

Clinical Trials and Comparative Effectiveness

In a comparative study published in the Journal of Rheumatology, diclofenac gel was found to be as effective as oral NSAIDs in providing pain relief for patients with osteoarthritis of the knee, while offering the advantage of lower systemic exposure and reduced risk of gastrointestinal side effects.