Description
Diclofenak natrium (diclofenac) Tablets 0.05 g. №10
Composition
Active Ingredient: Diclofenac sodium 0.05 g per tablet.
Mechanism of Action
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the production of prostaglandins, which are mediators of inflammation and pain in the body.
Pharmacological Properties
Diclofenac exhibits anti-inflammatory, analgesic, and antipyretic properties by blocking the enzyme cyclooxygenase, thus reducing the synthesis of prostaglandins.
Indications for Use
- Relief of pain and inflammation in arthritis
- Management of ankylosing spondylitis
- Treatment of acute gout
Contraindications
Avoid diclofenac tablets in individuals with:
- History of allergic reactions to NSAIDs
- Peptic ulcers
- Kidney problems
- Third trimester of pregnancy
Side Effects
Common side effects may include gastrointestinal disturbances, headache, dizziness, and skin reactions. Serious side effects like gastrointestinal bleeding and cardiovascular events are rare but possible.
Usage Instructions
Take 1 tablet 2-3 times daily with food. Swallow the tablet whole with water. Do not exceed the recommended dosage provided by your healthcare provider.
Benefits Compared to Analogues
Diclofenac has demonstrated efficacy in managing various inflammatory conditions with a favorable safety profile compared to other NSAIDs.
Suitable Patient Groups
Diclofenac can be used in adults, including the elderly, for the relief of pain and inflammation. It is not recommended for children without medical supervision.
Storage and Shelf Life
Store diclofenac tablets at room temperature, away from moisture and heat. Keep out of reach of children. Check the expiration date on the packaging before use.
Packaging Description
Diclofenac tablets are typically packaged in blister packs of 10 tablets each, ensuring convenient and accurate dosing.
Clinical Evidence and Proven Effectiveness
Diclofenac has been extensively studied in clinical trials, showing effectiveness in osteoarthritis, rheumatoid arthritis, and musculoskeletal disorders. Research indicates good tolerability and safety profile with a low incidence of severe adverse effects.
