Description
Diclofenak Ultra (Diclofenac) Gel 5% 50 g
Ingredients
Active ingredient: Diclofenac Sodium 5% w/w. Other ingredients: carbomer, cocoyl caprylocaprate, diethylamine, isopropyl alcohol, liquid paraffin, and purified water.
Mechanism of Action
Diclofenak Ultra gel exerts its pharmacological effects by inhibiting the enzyme cyclooxygenase (COX), thereby reducing the synthesis of prostaglandins. This inhibition leads to decreased inflammation, pain, and fever.
Pharmacological Properties
The active ingredient, diclofenac, belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It possesses analgesic, anti-inflammatory, and antipyretic properties. The gel formulation allows for targeted delivery of the medication to the site of application.
Indications for Use
Diclofenak Ultra gel is indicated for the relief of pain and inflammation associated with osteoarthritis, rheumatoid arthritis, sprains, strains, and backache. It is suitable for localized treatment of musculoskeletal conditions.
Contraindications
Avoid using Diclofenak Ultra gel if you have a known allergy to diclofenac or any other components of the gel. It is contraindicated for use on broken or irritated skin, as well as in the eye, mouth, or mucous membranes.
Side Effects
Common side effects of Diclofenak Ultra gel may include skin irritation, itching, or rash at the application site. In rare cases, systemic side effects such as gastrointestinal disturbances or hypersensitivity reactions may occur.
Usage Instructions
Apply a thin layer of Diclofenak Ultra gel to the affected area 3-4 times daily. Gently massage the gel into the skin until fully absorbed. Wash hands thoroughly after application. Use the gel externally only and avoid exceeding the recommended dosage.
Benefits Compared to Analogues
Diclofenak Ultra gel offers the advantage of localized treatment with reduced systemic absorption compared to oral NSAIDs. This targeted approach minimizes the risk of gastrointestinal side effects commonly associated with systemic NSAID use.
Suitable Patient Groups
Diclofenak Ultra gel is suitable for adults, including the elderly, for the management of localized pain and inflammation. It is not recommended for use in children without medical supervision. Pregnant or breastfeeding individuals should consult a healthcare professional before use.
Storage and Shelf Life
Store Diclofenak Ultra gel at room temperature, away from direct sunlight and moisture. Check the expiration date on the packaging and do not use the gel beyond the indicated shelf life.
Packaging Description
Diclofenak Ultra gel is available in a 50 g tube for topical application. The packaging should be sealed and tamper-evident upon purchase. Keep the tube tightly closed when not in use.
Scientific Evidence
Diclofenak Ultra gel has been the subject of extensive clinical studies evaluating its efficacy in managing pain and inflammation. Research published in the Journal of Pain Research demonstrated the superior pain relief provided by diclofenac gel compared to a placebo in patients with osteoarthritis.
Additional Information
Diclofenak Ultra gel’s mechanism of action involves the inhibition of prostaglandin synthesis, leading to reduced pain and inflammation at the site of application. Clinical trials have shown that the gel is well-tolerated and effective in treating various musculoskeletal conditions, with a favorable safety profile compared to systemic NSAIDs.
