Description

Difors 80 (Amlodipine Besilate and Valsartan) Coated Tablets 5 mg/80 mg. №30

Ingredients:

Each tablet contains 5 mg of amlodipine besilate and 80 mg of valsartan.

Mechanism of Action:

Amlodipine inhibits calcium ion influx across cell membranes, leading to vasodilation and decreased peripheral vascular resistance. Valsartan, an angiotensin II receptor blocker, blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II, further reducing blood pressure.

Pharmacological Properties:

The combination of amlodipine besilate and valsartan in Difors 80 tablets provides a synergistic effect in lowering blood pressure.

Indications for Use:

Difors 80 tablets are indicated for the treatment of hypertension in patients not adequately controlled with monotherapy.

Contraindications:

Avoid using Difors 80 if pregnant, have severe liver disease, or are allergic to any tablet components.

Side Effects:

Side effects are similar to those of individual components with no significant additional adverse effects reported.

Usage Instructions:

Take one tablet daily, with or without food, at the same time each day.

Benefits Compared to Analogues:

Difors 80 offers the convenience of a single pill combination therapy, potentially improving medication adherence.

Suitable Patient Groups:

Difors 80 is suitable for adult patients with hypertension.

Storage Conditions and Shelf Life:

Store in a cool, dry place. Check the expiration date on the packaging.

Packaging Description:

Difors 80 is available in a pack of 30 coated tablets.

Scientific Evidence:

Studies have shown that the combination of amlodipine besilate and valsartan in Difors 80 tablets is more effective in reducing blood pressure compared to monotherapy.