Description

Difosfocin (Citicoline) Solution for Injections 500 mg/4 ml. 4 ml Ampoules №5

Ingredients:

Each 4 ml ampoule contains 500 mg of Citicoline.

Dosage:

The usual dosage is 500 mg (1 ampoule) administered via intramuscular or intravenous injection once daily.

Indications:

Difosfocin is indicated for the treatment of acute ischemic stroke, traumatic brain injury, and cognitive disorders of vascular origin.

Contraindications:

Do not use Difosfocin in patients with hypersensitivity to Citicoline or any other component of the formulation.

Directions:

Administer the solution for injections as directed by a healthcare professional. Do not exceed the recommended dosage.

Scientific Evidence:

Citicoline, the active ingredient in Difosfocin, has shown promising results in various studies for its neuroprotective and cognitive-enhancing effects. Research published in the Journal of Neurology and Neuroscience demonstrated that Citicoline supplementation improved cognitive function and memory in patients with mild cognitive impairment.

Furthermore, a meta-analysis published in the International Journal of Stroke concluded that Citicoline treatment significantly reduced the neurological deficit in patients with acute ischemic stroke when compared to placebo, highlighting its efficacy in stroke management.

Additional Information:

• Pharmacological Action: Citicoline acts as a precursor to phospholipid synthesis in the brain, promoting neuronal membrane repair and enhancing neurotransmitter production, which may contribute to its neuroprotective effects.
• Comparative Effectiveness: Compared to other cognitive enhancers, Citicoline has been reported to have a favorable safety profile and a lower risk of side effects, making it a preferred choice in the management of cognitive disorders.