Description

Diocor 80 (valsartan, hydrochlorothiazide) Coated Tablets 80 mg/12.5 mg. №30

Ingredients

Diocor 80 tablets contain 80 mg of valsartan and 12.5 mg of hydrochlorothiazide. These active ingredients work together to lower blood pressure by relaxing blood vessels and increasing urine output.

Dosage

The recommended dosage of Diocor 80 is one tablet once daily. It is important to follow the prescribed dosage and not exceed it without medical advice.

Indications

Diocor 80 tablets are indicated for the treatment of hypertension in patients who require initial therapy or are not adequately controlled on monotherapy.

Contraindications

Do not use Diocor 80 if you are pregnant, have severe renal impairment, or are allergic to any of the ingredients. It is important to consult a healthcare provider before starting this medication.

Directions

Take Diocor 80 tablets orally with or without food as directed by your doctor. It is essential to take the medication regularly to experience its full benefits.

Scientific Evidence

Studies have shown that the combination of valsartan and hydrochlorothiazide in Diocor 80 tablets is effective in lowering blood pressure. Research published in the Journal of Clinical Hypertension demonstrated a significant reduction in both systolic and diastolic blood pressure levels with this combination therapy.

Additional Information

In addition to lowering blood pressure, Diocor 80 tablets may also offer renal protective effects due to the actions of valsartan. This medication has been well-tolerated in clinical trials, with common side effects including dizziness and fatigue.

Pharmacological Effects: Valsartan works by blocking the action of angiotensin II, a hormone that constricts blood vessels, while hydrochlorothiazide increases urine output, reducing the volume of fluid in the blood vessels. This dual action helps to lower blood pressure effectively.

Clinical Trials: A randomized controlled trial published in the American Journal of Hypertension compared the efficacy of valsartan and hydrochlorothiazide combination therapy with other antihypertensive agents. The study concluded that the combination was superior in reducing blood pressure levels and well-tolerated by patients.