Description
Diulok (Duloxetine) Enteric Capsules 60 mg. №30
Composition
Each enteric capsule contains 60 mg of duloxetine.
Mechanism of Action
Duloxetine, the active ingredient in Diulok capsules, is a selective serotonin and norepinephrine reuptake inhibitor (SNRI). It works by increasing the levels of serotonin and norepinephrine in the brain, which are neurotransmitters involved in regulating mood and pain perception.
Pharmacological Properties
Duloxetine acts by inhibiting the reuptake of serotonin and norepinephrine, thereby prolonging their effects in the synaptic cleft. This dual action on neurotransmitters contributes to its therapeutic efficacy in various conditions.
Indications for Use
Diulok (duloxetine) enteric capsules are indicated for the treatment of major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain.
Contraindications
Avoid using Diulok (duloxetine) enteric capsules if you have uncontrolled narrow-angle glaucoma or are taking a monoamine oxidase inhibitor (MAOI) due to the risk of serious drug interactions.
Side Effects
Common side effects of Diulok capsules may include nausea, dry mouth, dizziness, and fatigue. If you experience severe side effects or signs of an allergic reaction, seek immediate medical attention.
Usage Instructions
The recommended dosage is one 60 mg enteric capsule daily. Swallow the capsule whole with water, without crushing or chewing it. Take it with or without food as advised by your healthcare provider.
Benefits Compared to Analogues
Diulok (duloxetine) offers advantages over other medications in its class by providing dual inhibition of serotonin and norepinephrine reuptake, leading to improved management of depressive symptoms and pain conditions.
Suitable Patient Groups
Diulok capsules are suitable for adult patients with major depressive disorder, anxiety disorders, neuropathic pain, and chronic pain conditions. Dosage adjustments may be necessary for elderly individuals or those with renal impairment.
Storage and Shelf Life
Store Diulok (duloxetine) enteric capsules in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use beyond the stated shelf life.
Packaging Description
Each package contains 30 enteric capsules of 60 mg strength. The capsules are sealed in blister packs to maintain their integrity and protect them from environmental factors.
Clinical Evidence and Proven Effectiveness
Several clinical trials have demonstrated the efficacy of duloxetine in treating major depressive disorder, anxiety disorders, and chronic pain syndromes. For example, a study published in the Journal of Clinical Psychiatry highlighted the superior efficacy of duloxetine over placebo in reducing symptoms of major depression.
