Description
Eglonil (Sulpiride) Tablets 200 mg. №12
Ingredients
Active ingredient: Each tablet contains Sulpiride 200 mg.
Mechanism of Action
Sulpiride, the primary component of Eglonil, functions as a selective antagonist of dopamine D2 and D3 receptors. By modulating dopaminergic neurotransmission in the brain, it enhances the symptoms of patients with schizophrenia through its antipsychotic properties.
Pharmacological Properties
Sulpiride, a benzamide derivative, exerts its therapeutic effects by blocking postsynaptic dopamine receptors in the limbic system. This action leads to the normalization of dopamine-mediated neurotransmission, contributing to the alleviation of psychotic symptoms.
Indications for Use
Indicated for: Eglonil is prescribed for the management of various psychiatric conditions, including schizophrenia and depressive episodes associated with psychotic disorders.
Contraindications
Do not use Eglonil if:
- You have a known hypersensitivity to sulpiride or any other tablet components.
- You have a history of neuroleptic malignant syndrome.
- You are pregnant or breastfeeding.
Side Effects
Common side effects of Eglonil may include extrapyramidal symptoms, hyperprolactinemia, drowsiness, and gastrointestinal disturbances. Monitoring for adverse reactions is crucial during treatment.
Usage Instructions
Dosage: The typical dosage ranges from 200 to 800 mg daily, administered in 2 to 3 divided doses. It is essential to follow the dosing regimen prescribed by your healthcare provider for optimal therapeutic outcomes.
Benefits Compared to Analogues
Eglonil offers advantages over traditional antipsychotic medications due to its selective dopaminergic receptor blockade, potentially reducing the risk of certain adverse effects commonly associated with typical antipsychotics.
Suitable Patient Groups
Eglonil can be safely administered to adult patients, including the elderly population, under appropriate medical supervision. Use in pediatric patients should be determined based on individual clinical assessments.
Storage and Shelf Life
Store Eglonil tablets in a cool, dry place, shielded from direct sunlight. Ensure that the product remains out of children’s reach. Check the expiration date on the packaging and avoid using expired tablets.
Packaging Description
Eglonil is available in blister packs containing 12 tablets, each labeled with the medication name, strength, and dosage information for clear identification.
Clinical Evidence and Proven Effectiveness
Pharmacological effects: Sulpiride, the active ingredient in Eglonil, exerts its antipsychotic action by selectively blocking dopamine receptors, resulting in improved symptoms in patients with schizophrenia.
Clinical trials: Research studies, including the work of Moller et al. (2005), have demonstrated the efficacy of sulpiride in alleviating positive and negative symptoms of schizophrenia when compared to a placebo, with a favorable side effect profile.
Additional Information
It is essential to maintain regular follow-up appointments with your healthcare provider while undergoing Eglonil therapy to monitor treatment response and adjust the dosage if necessary. In case of severe side effects or allergic reactions, seek immediate medical attention.
