Description
Enap (Enalapril Maleate) Tablets 10 mg. №20
Composition
Each tablet contains 10 mg of enalapril maleate as the active ingredient.
Mechanism of Action
Enalapril, an ACE inhibitor, works by inhibiting the angiotensin-converting enzyme, leading to vasodilation and reduced aldosterone secretion. This mechanism results in lowered blood pressure and improved cardiac function.
Pharmacological Properties
Enap tablets contain enalapril maleate, which is rapidly absorbed in the body and converted to enalaprilat, the active form. Enalaprilat inhibits ACE, leading to reduced angiotensin II levels and decreased aldosterone secretion, resulting in vasodilation and decreased blood pressure.
Indications for Use
Enap tablets are indicated for the treatment of hypertension, heart failure, and to improve survival after a heart attack.
Contraindications
Do not use Enap if you are allergic to enalapril or any other ACE inhibitor. It is contraindicated in pregnancy due to the potential harm it may cause to the fetus.
Side Effects
Common side effects of Enap may include dizziness, cough, and low blood pressure. If you experience severe side effects, seek medical attention promptly.
Usage Instructions
The usual starting dose of Enap is 5 mg once daily. The dosage may be adjusted by your healthcare provider to between 10-40 mg per day based on your condition.
Benefits Compared to Analogues
Enap has demonstrated efficacy in managing hypertension and heart failure through its ACE inhibition mechanism. Compared to other ACE inhibitors, Enap has shown to be effective in improving cardiac function and reducing blood pressure with a lower risk of certain side effects.
Suitable Patient Groups
Enap is suitable for adult patients with hypertension, heart failure, or those needing post-heart attack care. Dosage adjustments may be necessary for elderly patients or those with impaired renal function.
Storage and Shelf Life
Store Enap tablets in a cool, dry place away from direct sunlight. Check the expiry date on the packaging and do not use the tablets if expired.
Packaging Description
Enap tablets are packaged in blister packs of 20 tablets each. The packaging is designed to protect the tablets from moisture and ensure their integrity until use.
Clinical Evidence and Proven Effectiveness
Enalapril, the active ingredient in Enap tablets, has been extensively studied and proven effective in managing hypertension and heart failure. Clinical trials have shown that Enap can reduce blood pressure, improve cardiac function, and increase survival rates in patients with heart conditions.
