Description
Epirubicin Medak (epirubicin) Solution for Injections 2 mg/ml – Vial 50 ml
Composition
Epirubicin Medak contains the active ingredient epirubicin hydrochloride as a solution for injections. Other ingredients may include water for injections and dilute hydrochloric acid.
Mechanism of Action
Epirubicin Medak exerts its pharmacological effects by interfering with the DNA replication process in cancer cells, ultimately leading to cell death. This mechanism of action makes it a valuable component in chemotherapy regimens for various malignancies.
Pharmacological Properties
Epirubicin Medak is a cytotoxic anthracycline antibiotic that inhibits topoisomerase II enzyme activity, disrupting DNA and RNA synthesis in cancer cells.
Indications for Use
Epirubicin Medak is indicated for the treatment of various cancers, including breast cancer, gastric cancer, and lung cancer. It is often used in combination with other chemotherapy medications to inhibit cancer cell growth.
Contraindications
Epirubicin Medak is contraindicated in patients with a history of severe allergic reactions to anthracyclines, severe bone marrow suppression, and severe liver impairment. It should not be used during pregnancy or breastfeeding.
Side Effects
Common side effects of Epirubicin Medak may include nausea, vomiting, hair loss, myelosuppression, and mucositis. Patients may also experience cardiotoxicity and infusion site reactions.
Usage Instructions
Epirubicin Medak is administered intravenously under the supervision of a healthcare professional. The dosage is individualized based on the patient’s body surface area and overall health condition. It is essential to follow the prescribed dosage and administration schedule strictly.
Benefits Compared to Analogues
Epirubicin Medak has been compared to other anthracycline drugs in clinical trials, demonstrating similar efficacy but potentially fewer side effects. Its well-established safety profile and proven effectiveness make it a preferred choice in oncology practice.
Suitable Patient Groups
Epirubicin Medak is suitable for adult patients with various types of cancers. Dosing adjustments may be required for pediatric and elderly patients based on their individual health status and tolerance to treatment.
Storage and Shelf Life
Epirubicin Medak should be stored at controlled room temperature away from light and moisture. The shelf life of the product is as indicated on the packaging.
Packaging Description
Epirubicin Medak is supplied in vials containing a sterile solution for injections. Each vial is labeled with the product name, concentration, and volume for accurate dosing.
Clinical Evidence and Proven Effectiveness
Studies have shown that epirubicin, the active ingredient in Epirubicin Medak, is effective in treating various types of cancer. Research published in the Journal of Clinical Oncology demonstrated the efficacy of epirubicin in improving survival rates in patients with advanced breast cancer.
