Gliteik 400 mg. Vial №1

Description

Gliteik Composition
active substance: teicoplanin;

1 bottle contains teicoplanin 400.0 mg;

excipient: sodium chloride;

solvent: water for injection.

Gliteik Dosage form.

Lyophilisate for solution for injection.

Basic physical and chemical properties: porous white mass with a brownish-yellow tint.

Gliteik Pharmacotherapeutic group.

Glycopeptide antibiotics. ATX code J01X A02.

Pharmacological properties

Pharmacodynamics.

Teicoplanin is a systemic glycopeptide antibiotic, a fermentation product of Actinoplanes teichomyceticus, which has bactericidal activity against aerobic and anaerobic Gram-positive bacteria. Teicoplanin inhibits the growth of sensitive microorganisms by interfering with the biosynthesis of cell membranes at sites that are different from the sites of action of beta-lactam antibiotics.

Antimicrobial spectrum. The limiting concentrations that make it possible to differentiate susceptible strains (S) from strains with moderate sensitivity, and strains with moderate sensitivity from resistant strains (R), are as follows: S ≤ 4 mg / L and R ˃ 16 mg / L.

The prevalence of acquired resistance to this drug in some pathogen species may vary by geographic region and time. Therefore, it is useful to have information on the local prevalence of resistance, especially when treating severe infections. These data are only general guidelines indicating the likelihood of a particular bacterial strain being susceptible to this antibiotic.

Indications
Infections caused by gram-positive bacteria, including those sensitive or resistant to methicillin, as well as those who are allergic to beta-lactam antibiotics. Adults. Treatment:

infections of the skin and soft tissues;
upper and lower urinary tract infections with and without complications;
respiratory tract infections;
ear, throat, nose infections;
infections of bones and joints;
septicemia;
endocarditis;
peritonitis associated with continuous peritoneal dialysis on an outpatient basis.
Prevention. Prevention of infective endocarditis in case of allergy to beta-lactam antibiotics:

in dentistry or in upper respiratory tract procedures used under general anesthesia;
during surgical interventions on the genitourinary and gastrointestinal tract.
Children (except newborns).

Treatment:

infections of the skin and soft tissues;
upper and lower urinary tract infections with and without complications;
respiratory tract infections;
ear, throat, nose infections;
infections of bones and joints; septicemia.

Contraindications
Hypersensitivity to teicoplanin. Newborns. The use of this medication while breastfeeding is not recommended (see section “Use during pregnancy or lactation”).