Gliucosat solution for injections 2 ml. ampoules №5

Description

GLIUCOSAT AMPOULES COMPOSITION

active substance: glucosamine sulfate sodium chloride 2 ml solution (ampoule A) contains glucosamine sulfate sodium chloride 502.5 mg, equivalent to: glucosamine sulfate 400 mg and sodium chloride 102.5 mg excipients: lidocaine hydrochloride, water for injection solvent (ampoule C) contains excipients: diethanolamine, water for injection.

GLIUCOSAT AMPOULES DOSAGE FORM

Solution for injection.

GLIUCOSAT AMPOULES MAIN PHYSICAL AND CHEMICAL PROPERTIES:

ampoule A made of brown transparent glass contains a colorless or light yellow transparent liquid; ampoule B (solvent) made of colorless transparent glass contains a colorless transparent liquid; ampoule A + B (solution for injection) – transparent colorless or light yellow solution.

PHARMACOLOGICAL GROUP

Non-steroidal anti-inflammatory drugs. ATX code M01A X05.

PHARMACOLOGICAL PROPERTIES

Pharmacological. The active ingredient glucosamine sulfate is a salt of the amino monosaccharide glucosamine, which is present in the human body under physiological conditions and is used together with sulfates for the biosynthesis of hyaluronic acid in synovial fluid and glycosaminoglycans of the main substance of articular cartilage. Thus, the mechanism of action of glucosamine sulfate is to stimulate the synthesis of glycosaminoglycans and articular proteoglycans. In addition, glucosamine has an anti-inflammatory effect and inhibits the process of destruction of articular cartilage, mainly due to the manifestation of its own metabolic properties, the ability to suppress the activity of interleukin 1 (IL-1), which, on the one hand, affects the symptoms of osteoarthritis, and on the other hand, delays structural damage. joints, as evidenced by data from long-term clinical studies. According to initial in vitro and in vivo studies, exogenous administration of glucosamine sulfate stimulates proteoglycan biosynthesis, which is insufficient in osteoarthritis, promotes the fixation of sulfur ions during glycosaminoglycan synthesis, and improves trophic articular cartilage.

INDICATIONS

Treatment of osteoarthritis symptoms: pain and functional limitation.

CONTRAINDICATIONS

Hypersensitivity to the active substance or to any of the excipients, a tendency to bleeding.