Ibunorm Baby suspension 100 mg/5 ml. 100 ml.

$6.90

Manufacturer: Ukraine

Traitement symptomatique des maux de tête et des maux de dents, dysménorrhée, névralgie, maux de dos, articulations, muscles, douleurs rhumatismales, ainsi que des symptômes du rhume et de la grippe.

Category:

Description

Ibunorm Baby 100 ml Composition
active substance: 5 ml of the drug contain ibuprofen 100 mg;

Ibunorm Baby 100 ml excipients:

sorbitol (E 420) polysorbate 80 sodium phosphate anhydrous acid citric monohydrate, xanthan gum; glycerin sodium saccharin methylparaben (E 218) propylparaben (E 216) “Red orange” flavoring containing ethanol 96%, triacetin, orange essential oil, natural orange extract, natural aromatic compounds (aldehydes and esters), butylhydroxyanisole (E 320) purified water …

Ibunorm Baby 100 ml Dosage form
Oral suspension.

Basic physical and chemical properties: white or almost white suspension with a specific odor.

Pharmacotherapeutic group
Non-steroidal anti-inflammatory drugs. Propionic acid derivatives. ATX code М01А Е01.

Pharmacodynamics
Ibuprofen is an NSAID (NSAID) derivative of propionic acid that has been shown to be effective by inhibiting prostaglandin synthesis. In humans, ibuprofen reduces inflammation pain, swelling, and fever. Ibuprofen has analgesic, antipyretic and anti-inflammatory effects. It has been demonstrated that the onset of the analgesic and antipyretic effect of ibuprofen occurs within 30 minutes. In addition, ibuprofen inversely inhibits platelet aggregation.

Experimental evidence suggests that ibuprofen can suppress the effect of a low dose of acetylsalicylic acid (aspirin) on platelet aggregation when these drugs are used concomitantly. In a study where a single dose of 400 mg ibuprofen was taken within 8 hours before or within 30 minutes after taking immediate release acetylsalicylic acid (81 mg), there was a reduced effect of acetylsalicylic acid on thromboxane formation or platelet aggregation. However, the limitations of these data and uncertainty regarding the extrapolation of ex vivo data to the clinical picture does not allow making clear conclusions regarding the systematic use of ibuprofen. Therefore, with the occasional use of ibuprofen, such clinically significant effects are considered unlikely.

Pharmacokinetics
Ibuprofen is rapidly absorbed after ingestion and is rapidly distributed throughout the body. Excretion is rapid and complete and renal elimination.

The maximum concentration in blood plasma is reached 45 minutes after ingestion of the drug on an empty stomach. When taken with food, peak levels are observed after 1–2 hours. This time may vary for different dosage forms.

The half-life is approximately 2 hours. In limited studies, ibuprofen has been found in breast milk at very low concentrations.

Indications
Symptomatic treatment of fever and pain of various origins in children aged 3 months to 12 years with a body weight of at least 5 kg (including fever after immunization, acute respiratory viral infections, influenza, pain during teething, pain after tooth extraction, toothache, headache, sore throat, sprain pain and other types of pain, including inflammatory genesis).

Contraindications
Hypersensitivity to ibuprofen or to any of the other components of the drug.

A history of hypersensitivity reactions (eg, asthma, rhinitis, Quincke’s edema, urticaria) after using ibuprofen, acetylsalicylic acid (aspirin), or other non-steroidal anti-inflammatory drugs (NSAIDs).

Peptic ulcer and duodenal ulcer / bleeding in active form or relapses in history (two or more severe episodes of confirmed peptic ulcer or bleeding).

A history of gastrointestinal bleeding or perforation of the wall of the gastrointestinal tract associated with the use of NSAIDs.

Severe heart failure, severe liver failure, or severe renal failure.

Cerebrovascular or other bleeding.

Hematopoiesis or blood clotting disorders.

Hereditary fructose intolerance.