Ibuprom coated tablets 200 mg. №10

Description

Ibuprom №10 Storage:

active substance: ibuprofen

1 tablet contains ibuprofen 200 mg

Ibuprom №10 Excipients:

cellulose powdered starch corn starch pregelatinized guar gum talc crospovidone (type A) silicon dioxide colloidal aqueous oil vegetable hydrogenated hydroxypropylcellulose AS polyethylene glycol (macrogol 400) carcinate 7000 (titanium dioxide (E 171) sucrose sodium benzoate (E 211)) carnauba wax.

Ibuprom №10 Dosage form.

The tablets are coated.

Main physical and chemical properties: round biconvex tablets are covered with a white sugar shell.

Pharmacotherapeutic group. Non-steroidal anti-inflammatory and anti-rheumatic drugs. Derivatives of propionic acid.

Code ATX M01A E01.

Pharmacological properties.

Pharmacodynamics.

Pharmacokinetics.

Clinical characteristics.

Indication.

Contraindication.

-Hypersensitivity to ibuprofen or to any of the components of the drug.

-Gastric ulcer / bleeding in active form or recurrence in the anamnesis (two or more pronounced episodes of peptic ulcer disease or bleeding).

-Use of the drug with concomitant nonsteroidal anti-inflammatory drugs, including specific inhibitors of cyclooxygenase-2.

-Severe liver dysfunction, heart failure.

-Last trimester of pregnancy.

-Cerebrovascular or other bleeding.

-Disorders of hematopoiesis or blood clotting.

Interaction with other drugs and other types of interactions.

Ibuprofen as well as other NSAIDs should not be used in combination with:

– aspirin as it may increase the risk of side effects except when aspirin (dose not exceeding 75 mg per day) is prescribed by a doctor

– other NSAIDs, including selective inhibitors of cyclooxygenase-2.

Ibuprofen should be used with caution in combination with:

anticoagulants: NSAIDs may increase the therapeutic effect of anticoagulants such as warfarin

antihypertensives (ACE inhibitors and angiotensin II antagonists) and diuretics: NSAIDs may reduce the effect of diuretics and other antihypertensive drugs. In some patients with impaired renal function (eg in patients with dehydration or in elderly patients with impaired renal function), concomitant use of an ACE inhibitor or angiotensin II antagonist and drugs that inhibit cyclooxygenase may lead to further deterioration of renal function, including possible acute renal failure. reversible. Therefore, such combinations should be prescribed with caution, especially in elderly patients. If long-term treatment is required, the patient should be adequately hydrated and considered
on monitoring renal function at the beginning of combination treatment and with a certain frequency in the future. Diuretics may increase the risk of nephrotoxic effects of NSAIDs.