Description
Ilomedin Concentrate for Infusions 20 mcg/ml. 1ml. №5
Composition
Ilomedin concentrate for infusions contains the active ingredient iloprost at a concentration of 20 mcg/ml. Other ingredients may include sodium chloride, hydrochloric acid, and water for injections.
Mechanism of Action
Ilomedin is a synthetic analogue of prostacyclin, a potent vasodilator and inhibitor of platelet aggregation. It acts by dilating blood vessels, improving blood flow, and reducing platelet aggregation, which is beneficial in conditions like peripheral arterial occlusive disease (PAOD) and Raynaud’s phenomenon.
Pharmacological Properties
The pharmacological properties of Ilomedin concentrate for infusions stem from the vasodilatory and antiplatelet effects of iloprost. These properties contribute to enhanced blood flow and reduced platelet aggregation, aiding in the management of PAOD and Raynaud’s phenomenon.
Indications for Use
Ilomedin concentrate for infusions is indicated for the treatment of peripheral arterial occlusive disease (PAOD) and Raynaud’s phenomenon. It helps improve blood flow and relieve symptoms associated with these conditions.
Contraindications
Ilomedin concentrate for infusions is contraindicated in patients with known hypersensitivity to iloprost or any of the other ingredients in the formulation. It should not be used in patients with severe coronary heart disease, unstable angina pectoris, or acute myocardial infarction.
Side Effects
Common side effects of Ilomedin concentrate for infusions may include headache, flushing, nausea, vomiting, and hypotension. Patients should be monitored for any adverse reactions during treatment.
Usage Instructions
Ilomedin concentrate for infusions is administered intravenously. The recommended dosage is determined by the healthcare provider based on the patient’s condition. It is crucial to follow the prescribed dosage and administration instructions carefully.
Benefits Compared to Analogues
Compared to other treatment options, Ilomedin concentrate for infusions offers a targeted approach to improving blood flow and reducing symptoms in patients with PAOD and Raynaud’s phenomenon. Its vasodilatory and antiplatelet effects set it apart from conventional therapies.
Suitable Patient Groups
Ilomedin concentrate for infusions is suitable for adult patients with PAOD and Raynaud’s phenomenon who do not have contraindications to iloprost. Special care should be taken when considering its use in pediatric and elderly populations.
Storage and Shelf Life
It is important to store Ilomedin concentrate for infusions as per the manufacturer’s instructions to maintain its stability and efficacy. The product should be stored in a cool, dry place away from direct sunlight. Check the expiration date before use.
Packaging Description
Ilomedin concentrate for infusions is available in packs containing 5 vials of 1ml each. The packaging is designed to ensure the integrity and sterility of the product until the time of use.
Clinical Evidence and Proven Effectiveness
Studies have shown the efficacy of iloprost in improving symptoms and quality of life in patients with PAOD and Raynaud’s phenomenon. Research by Fagrell et al. (1999) demonstrated significant improvement in pain-free walking distance and ulcer healing with iloprost treatment.
