Description
Indometacin Sofarma Ointment 10% 40 g. Tube
Ingredients
Active ingredient: Indometacin 10%
Other ingredients: Propylene glycol, cetostearyl alcohol, liquid paraffin, white soft paraffin.
Mechanism of Action
Indometacin works by inhibiting the production of prostaglandins, which are substances in the body that cause pain and inflammation. By reducing the levels of prostaglandins, indometacin helps alleviate symptoms such as swelling, pain, and stiffness.
Pharmacological Properties
Indometacin Sofarma Ointment exhibits anti-inflammatory, analgesic, and antipyretic properties. It acts by blocking the enzyme cyclooxygenase, thereby reducing the synthesis of prostaglandins involved in the inflammatory process.
Indications for Use
Indometacin Sofarma Ointment is indicated for the relief of pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and soft tissue injuries.
Contraindications
Avoid using Indometacin Sofarma Ointment if you are allergic to indometacin or any other ingredients in the ointment. It is contraindicated for use on broken or infected skin.
Side Effects
Common side effects of Indometacin Sofarma Ointment may include skin irritation, redness, or rash at the application site. In rare cases, systemic effects such as gastrointestinal disturbances or allergic reactions may occur.
Usage Instructions
Clean and dry the affected area before applying a thin layer of the ointment. Massage gently until fully absorbed. Use 2-3 times daily for adults. Children should only use under medical supervision.
Benefits Compared to Analogues
Compared to oral nonsteroidal anti-inflammatory drugs (NSAIDs), Indometacin Sofarma Ointment offers localized pain relief with potentially fewer systemic side effects. Its topical application targets the affected area directly, minimizing systemic exposure.
Suitable Patient Groups
Indometacin Sofarma Ointment is suitable for adults with musculoskeletal conditions such as arthritis. Children should use this ointment only under the guidance of a healthcare provider.
Storage and Shelf Life
Store the ointment in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product if expired.
Packaging Description
Indometacin Sofarma Ointment is supplied in a 40 g tube for topical application. The packaging should be intact and sealed before first use.
Clinical Evidence and Proven Effectiveness
Studies have demonstrated the efficacy of topical indometacin formulations in reducing pain and inflammation in various musculoskeletal conditions. Research published in the Journal of Rheumatology and the Journal of Clinical Pharmacology supports the effectiveness of indometacin ointment in improving pain and function in patients with arthritis.
