Description

Indometacin Sofarma Ointment 10% 40 g. Tube

Ingredients

Active ingredient: Indometacin 10%
Other ingredients: Propylene glycol, cetostearyl alcohol, liquid paraffin, white soft paraffin.

Dosage

Adults: Apply a thin layer to the affected area 2-3 times a day.
Children: Use under medical supervision only.

Indications

Indometacin Sofarma Ointment is indicated for the relief of pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and soft tissue injuries.

Contraindications

Do not use Indometacin Sofarma Ointment if you are allergic to indometacin or any other ingredients in the ointment. Avoid use on broken or infected skin.

Directions

Clean and dry the affected area before applying the ointment. Gently massage a small amount into the skin until fully absorbed. Wash hands after application.

Scientific Evidence

Studies have shown that topical indometacin formulations can provide effective pain relief and reduce inflammation in various musculoskeletal conditions. Research published in the Journal of Rheumatology demonstrated the efficacy of indometacin ointment in reducing pain and improving function in patients with osteoarthritis.

Additional Information

It is important to follow the recommended dosage and not exceed the prescribed frequency of application. Avoid contact with eyes and mucous membranes. Consult a healthcare professional before using this ointment, especially if you have any underlying medical conditions or are pregnant or breastfeeding.

Pharmacological Effects: Indometacin works by inhibiting the production of prostaglandins, which are substances in the body that cause pain and inflammation. By reducing the levels of prostaglandins, indometacin helps alleviate symptoms such as swelling, pain, and stiffness.

Clinical Trials: Clinical trials have shown that indometacin ointment can be as effective as oral nonsteroidal anti-inflammatory drugs (NSAIDs) in providing local pain relief with fewer systemic side effects. A study published in the Journal of Clinical Pharmacology compared the efficacy of indometacin ointment with oral indometacin in patients with knee osteoarthritis, showing similar pain reduction and improved joint function with topical application.