Infors coated tablets 100 mg. №8

Description

Infors №8 Composition
Active substance: sildenafil;

1 coated tablet contains 70.24 mg of sildenafil citrate, which is equivalent to 50 mg of sildenafil;

1 coated tablet contains sildenafil citrate 140.48 mg, which is equivalent to sildenafil 100 mg;

Excipients: microcrystalline cellulose, anhydrous calcium hydrogen phosphate, povidone, croscarmellose sodium, magnesium stearate, Opadrai blue 03A205003 (hypromellose, microcrystalline cellulose, macrogol stearate, titanium dioxide (E 171), brilliant blue polyethylene (E 133)

Infors №8 Contraindications
Hypersensitivity to the active substance or any of the excipients of the drug.
Concomitant use with nitric oxide donors (such as amyl nitrite) or nitrates in any form is contraindicated, since it is known that sildenafil affects the pathways of nitric oxide / cyclic guanosine monophosphate (cGMP) metabolism and potentiates the hypotensive effect of nitrates.
The simultaneous use of PDE-5 inhibitors (including sildenafil) with guanylate cyclase stimulants, such as riociguat, is contraindicated because it can lead to symptomatic hypotension.
Conditions for which sexual activity is not recommended (for example, severe cardiovascular disorders such as unstable angina or severe heart failure).
Loss of vision in one eye due to non-arterial anterior ischemic neuropathy of the optic nerve, regardless of whether this pathology is associated with previous use of PDE-5 inhibitors or not.
The presence of such diseases: severe liver dysfunction, arterial hypotension (blood pressure below 90/50 mm Hg).
Recently suffered stroke or myocardial infarction and known hereditary degenerative retinal diseases such as retinitis pigmentosa (a small number of such patients have genetic disorders of the retinal PDE), since the safety of sildenafil has not been studied in the case of such diseases.

Mode of application
The drug is administered orally.

The drug should be used immediately after the tablet is removed from the blister. The tablet should be put on the tongue, wait for it to disintegrate, and then swallowed. The drug can be taken with or without water.

If it is necessary to use a dose of 100 mg, the second tablet should be taken only after the first tablet has completely disintegrated.

It is recommended to use the drug on an empty stomach, since when the drug is used simultaneously with fatty foods, there is a significant delay in absorption compared to the use of tablets on an empty stomach.

Infors №8 Application features

Pregnant
Not intended for use by women.

Children
The drug is indicated for use by persons under the age of 18.

Drivers
Carefully.

Overdose
The use of sildenafil at a dose of 200 mg did not lead to an increase in efficacy, but caused an increase in the number of cases of adverse reactions (headache, flushing, dizziness, dyspepsia, nasal congestion, visual disturbances).

In case of overdose, if necessary, resort to the usual supportive measures. Acceleration of the clearance of sildenafil during hemodialysis is unlikely due to the high degree of binding of the drug to blood plasma proteins and the lack of elimination of sildenafil in the urine.