Description
Intagra ІS Coated Tablets 0.05 g. №4
Composition
Each coated tablet contains 0.05 g of the active ingredient Sildenafil Citrate.
Mechanism of Action
Intagra ІS works by inhibiting the enzyme phosphodiesterase type 5 (PDE5) in the corpus cavernosum of the penis. This inhibition leads to increased levels of cyclic guanosine monophosphate (cGMP), which promotes smooth muscle relaxation and vasodilation, allowing for increased blood flow to the penis during sexual stimulation.
Pharmacological Properties
Sildenafil Citrate, the active ingredient in Intagra ІS, is a selective and potent inhibitor of PDE5. It specifically targets the enzyme involved in the degradation of cGMP in the corpus cavernosum, leading to enhanced erectile response.
Indications for Use
Intagra ІS is indicated for the treatment of erectile dysfunction in adult men. It is used to improve erectile function and facilitate the achievement and maintenance of erections during sexual activity.
Contraindications
Intagra ІS is contraindicated in individuals who are taking nitrate medications due to the risk of severe hypotension. It is also contraindicated in patients with known hypersensitivity to Sildenafil Citrate or any other component of the product. Patients with severe hepatic impairment, severe renal impairment, or recent history of stroke or myocardial infarction should avoid the use of Intagra ІS.
Side Effects
- Common side effects may include headache, flushing, dyspepsia, nasal congestion, and dizziness.
- Less common side effects may include visual disturbances, palpitations, and priapism.
- Patients should seek medical attention if they experience prolonged or painful erections lasting more than 4 hours.
Usage Instructions
The recommended dose of Intagra ІS is one tablet (0.05 g) taken orally as needed, approximately 30 minutes to 1 hour before anticipated sexual activity. The tablet should be swallowed whole with a glass of water. Avoid consuming alcohol or grapefruit juice while using Intagra ІS to minimize the risk of adverse effects.
Benefits Compared to Analogues
Intagra ІS offers a rapid onset of action and prolonged duration of effect compared to other PDE5 inhibitors. It provides effective treatment for erectile dysfunction with a well-established safety profile and high patient satisfaction rates.
Suitable Patient Groups
Intagra ІS is intended for adult men with erectile dysfunction. It is not indicated for use in women or individuals under 18 years of age. Elderly patients can use Intagra ІS with caution, adjusting the dosage based on individual tolerance and comorbidities.
Storage and Shelf Life
Store Intagra ІS in a cool, dry place away from direct sunlight. Keep the tablets in their original packaging to protect them from moisture. Check the expiration date on the packaging and do not use the product beyond the stated shelf life.
Packaging Description
Intagra ІS is available in blister packs containing 4 coated tablets. Each tablet is individually sealed to maintain product integrity and ensure accurate dosing.
Clinical Evidence and Proven Effectiveness
Studies have demonstrated the efficacy of Sildenafil Citrate in improving erectile function in men with erectile dysfunction. Clinical trials have shown a significant increase in the ability to achieve and maintain erections with the use of Sildenafil compared to placebo. Research published in reputable journals supports the positive outcomes associated with the use of Intagra ІS in the management of erectile dysfunction.
