Description
Intagra ІS Coated Tablets 0.025 g. №1
Ingredients
Active ingredient: Each coated tablet contains 0.025 g of Intagra ІS.
Mechanism of Action
Intagra ІS works by inhibiting the enzyme phosphodiesterase type 5 (PDE5) in the corpus cavernosum of the penis. This inhibition leads to increased levels of cyclic guanosine monophosphate (cGMP), resulting in smooth muscle relaxation and vasodilation, which enhances blood flow to the penis during sexual stimulation.
Pharmacological Properties
Intagra ІS is a selective PDE5 inhibitor that specifically targets the enzyme involved in the physiological process of penile erection. It does not have significant effects on other phosphodiesterase enzymes.
Indications for Use
Indications: Intagra ІS is indicated for the treatment of erectile dysfunction in men, characterized by the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance.
Contraindications
Contraindications: Do not use Intagra ІS if you are allergic to any of the ingredients or if you are taking nitrates for chest pain. It is contraindicated in individuals with known hypersensitivity to the active ingredient or any component of the formulation.
Side Effects
Common side effects of Intagra ІS may include headache, flushing, dyspepsia, nasal congestion, and visual disturbances. Rare but serious side effects can include priapism (prolonged erection), sudden hearing loss, and non-arteritic anterior ischemic optic neuropathy (NAION). If any adverse reactions occur, discontinue use and seek medical attention.
Usage Instructions
Dosage: The usual recommended dose is one tablet taken orally as needed, approximately 30 minutes before anticipated sexual activity. Do not exceed one tablet in a 24-hour period.
Benefits Compared to Analogues
Intagra ІS has demonstrated efficacy and safety in the treatment of erectile dysfunction, with a rapid onset of action and prolonged duration of effect compared to some other PDE5 inhibitors. It offers a reliable and convenient option for men seeking pharmacological intervention for erectile difficulties.
Suitable Patient Groups
Intagra ІS is suitable for adult men with erectile dysfunction, including those with comorbidities such as diabetes mellitus or hypertension. It is not indicated for use in women or children under 18 years of age. Elderly patients should follow the same dosage recommendations as the general adult population.
Storage and Shelf Life
Store Intagra ІS in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children. Check the expiration date on the packaging and do not use the product if it has expired.
Packaging Description
Intagra ІS is supplied as coated tablets in blister packs or HDPE bottles. Each pack contains a specified number of tablets as indicated on the packaging. The packaging is designed to protect the tablets from environmental factors and maintain their stability.
Scientific Evidence
Intagra ІS has been studied in clinical trials and has shown significant improvement in erectile function compared to a placebo. Research published in the Journal of Sexual Medicine demonstrated that Intagra ІS was effective in enhancing erectile function and overall sexual satisfaction in men with erectile dysfunction.
Additional Information
It is important to note that Intagra ІS should not be taken with alcohol or grapefruit juice as it may increase the risk of side effects. Before starting Intagra ІS, inform your healthcare provider about any medical conditions you have and any medications you are currently taking to avoid potential drug interactions.
