Description
Intagra ІS Coated Tablets 0.05 g. №1
Ingredients
Each coated tablet contains 0.05 g of Intagra ІS.
Mechanism of Action
Intagra ІS contains sildenafil citrate, a phosphodiesterase type 5 (PDE5) inhibitor. By inhibiting PDE5, sildenafil enhances the effects of nitric oxide, leading to increased blood flow in the corpus cavernosum of the penis during sexual stimulation. This mechanism results in improved erectile function.
Pharmacological Properties
Sildenafil citrate, the active ingredient in Intagra ІS, selectively inhibits PDE5, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum. This action leads to prolonged vasodilation and increased blood flow, facilitating penile erection.
Indications for Use
Intagra ІS is indicated for the treatment of erectile dysfunction in adult men. It is intended for use in individuals who have difficulty achieving or maintaining an erection sufficient for satisfactory sexual performance.
Contraindications
Intagra ІS is contraindicated in individuals with a known hypersensitivity to sildenafil or any other components of the tablet. It should not be used concomitantly with nitrates, as this combination may potentiate the hypotensive effects of nitrates and sildenafil.
Side Effects
Common side effects of Intagra ІS may include headache, flushing, dyspepsia, nasal congestion, dizziness, and visual disturbances. In rare cases, serious adverse reactions such as priapism, sudden hearing loss, and cardiovascular events may occur. Patients should seek immediate medical attention if they experience any severe or persistent side effects.
Usage Instructions
The recommended dosage of Intagra ІS is one tablet (0.05 g) taken orally as needed, approximately 30 minutes before anticipated sexual activity. The tablet should be swallowed whole with a glass of water. Alcohol consumption and grapefruit juice should be avoided while using Intagra ІS to prevent potential interactions.
Benefits Compared to Analogues
Intagra ІS offers a rapid onset of action and a prolonged duration of effect compared to some other PDE5 inhibitors. Its flexible dosing regimen allows for on-demand use, providing greater spontaneity in sexual activities. Additionally, clinical studies have demonstrated its efficacy and safety in diverse patient populations.
Suitable Patient Groups
Intagra ІS is suitable for adult men diagnosed with erectile dysfunction. It may be used in various patient groups, including those with diabetes, hypertension, and mild to moderate renal impairment. However, special caution is advised in elderly patients and individuals with severe hepatic or renal dysfunction.
Storage and Shelf Life
Intagra ІS should be stored at room temperature (20-25°C) in a dry place away from direct sunlight and moisture. The shelf life of the product is typically 2 years from the date of manufacture. Unused tablets should be discarded properly according to local regulations.
Packaging Description
Intagra ІS is supplied in blister packs containing a specified number of coated tablets. The packaging is designed to protect the tablets from external factors that may affect their stability and efficacy. Each pack is labeled with essential information, including the name of the product, dosage strength, batch number, and expiry date.
Clinical Evidence and Proven Effectiveness
Clinical studies have shown that sildenafil, the active ingredient in Intagra ІS, is highly effective in improving erectile function and enhancing sexual satisfaction in men with erectile dysfunction. The drug’s rapid onset of action and favorable safety profile make it a preferred choice for many patients seeking treatment for this condition.
