Description
Intagra ІS Coated Tablets 0.025 g. №4
Ingredients
Intagra ІS tablets contain 0.025 g of the active ingredient sildenafil citrate. The tablets also include excipients such as microcrystalline cellulose, croscarmellose sodium, and magnesium stearate.
Mechanism of Action
Intagra ІS tablets act by inhibiting the enzyme phosphodiesterase type 5 (PDE5), leading to increased levels of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. This results in smooth muscle relaxation and vasodilation, enhancing blood flow to the penis during sexual stimulation and facilitating an erection.
Pharmacological Properties
The pharmacological properties of Intagra ІS tablets stem from the action of sildenafil citrate in increasing cGMP levels, ultimately promoting penile erection through improved blood circulation in response to sexual stimulation.
Indications for Use
Intagra ІS tablets are indicated for the treatment of erectile dysfunction in adult men. They work by increasing blood flow to the penis during sexual stimulation, aiding in achieving and sustaining an erection.
Contraindications
Intagra ІS tablets are contraindicated in individuals with a known hypersensitivity to sildenafil or any other component of the tablet. They should not be used in patients taking nitrates for chest pain or guanylate cyclase stimulators for pulmonary hypertension.
Side Effects
Common side effects of Intagra ІS tablets may include headache, flushing, dyspepsia, nasal congestion, dizziness, and visual disturbances. Patients should seek medical advice if these side effects persist or worsen.
Usage Instructions
Intagra ІS tablets should be taken orally as directed by a healthcare provider. The usual recommended dose is 50 mg taken as needed, approximately 1 hour before sexual activity. The maximum recommended dosing frequency is once per day.
Benefits Compared to Analogues
Compared to similar drugs, Intagra ІS tablets have demonstrated comparable efficacy in treating erectile dysfunction with a similar safety profile. Clinical trials have shown that sildenafil is well-tolerated and effective in improving erectile function across various causes of erectile dysfunction.
Suitable Patient Groups
Intagra ІS tablets are suitable for adult men with erectile dysfunction. Special caution should be exercised in patients with underlying cardiovascular conditions. The use of this medication in children and the elderly should be determined by a healthcare provider.
Storage and Shelf Life
Store Intagra ІS tablets in a cool, dry place away from direct sunlight. Keep them out of reach of children. Check the expiration date on the packaging and do not use the tablets if expired.
Packaging Description
Intagra ІS tablets are typically packaged in blister packs to protect them from moisture and ensure individual tablet integrity. Each pack contains a specified number of tablets as indicated on the packaging.
Scientific Evidence
Studies have shown the efficacy of sildenafil, the active ingredient in Intagra ІS tablets, in treating erectile dysfunction. A meta-analysis published in the Journal of Sexual Medicine concluded that sildenafil is a safe and effective treatment for erectile dysfunction, with a significant improvement in erectile function compared to placebo.
Additional Information
It is important to note that Intagra ІS tablets do not protect against sexually transmitted diseases. Patients with underlying cardiovascular conditions should consult their healthcare provider before using this medication. If an erection lasts longer than 4 hours, seek immediate medical attention to prevent long-term injury.
