Description
Ketalgyn (Ketorolac) Tablets 0.01g. №10
Composition
The active ingredient in Ketalgyn tablets is ketorolac. Each tablet contains 0.01g of ketorolac.
Mechanism of Action
Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits analgesic, anti-inflammatory, and antipyretic properties. It works by inhibiting the synthesis of prostaglandins through the inhibition of cyclooxygenase enzymes, thereby reducing pain and inflammation.
Pharmacological Properties
Ketorolac exerts its pharmacological effects by blocking the enzyme cyclooxygenase, thereby inhibiting prostaglandin synthesis. This results in decreased inflammation, pain, and fever. Ketorolac is rapidly and completely absorbed after oral administration, with peak plasma concentrations reached within 1-2 hours.
Indications for Use
Ketalgyn is indicated for the short-term management of moderate to severe acute pain that requires analgesia at the opioid level. It is suitable for patients requiring intense pain relief for a limited duration, such as postoperative pain or trauma-related pain.
Contraindications
- Patients with known hypersensitivity to ketorolac or any of its ingredients should not use Ketalgyn.
- Patients with active peptic ulcer disease, recent gastrointestinal bleeding, or perforation are contraindicated from using Ketalgyn.
- Patients with severe renal impairment or at risk of renal failure due to volume depletion should avoid Ketalgyn.
Side Effects
Common side effects of Ketalgyn may include gastrointestinal disturbances, such as nausea, indigestion, and gastric irritation. Other potential side effects include renal impairment, hypersensitivity reactions, and gastrointestinal ulcers. If any adverse reactions occur, discontinue use and consult a healthcare provider.
Usage Instructions
Take Ketalgyn orally with a full glass of water, with or without food. In case of stomach upset, it can be taken with food or milk. The recommended dosage is one tablet every 4 to 6 hours as needed for pain relief. Do not exceed 4 tablets in 24 hours. The dosage should be individualized based on the patient’s condition and response to treatment. It is important not to exceed the prescribed dose or duration of treatment.
Benefits Compared to Analogues
Ketalgyn offers effective pain relief comparable to opioid analgesics but with a lower risk of dependence and respiratory depression. It provides a safer alternative for managing moderate to severe pain without the potential for addiction commonly associated with opioids.
Suitable Patient Groups
Ketalgyn is suitable for adults and adolescents requiring short-term relief from moderate to severe pain. It is not recommended for use in children under a certain age (specify age limit if applicable) due to safety concerns. Elderly patients should use Ketalgyn with caution and may require dosage adjustments based on their renal function.
Storage and Shelf Life
Store Ketalgyn in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Check the expiration date on the packaging and do not use the product after the specified shelf life has passed.
Packaging Description
Ketalgyn is available in blister packs containing 10 tablets. Each tablet is individually sealed to maintain product integrity and ensure proper dosage control. The packaging is designed to protect the tablets from environmental factors that may affect their stability.
