Description
Ketanov (Ketorolac Tropetamine) Coated Tablets 10 mg. №10
Composition
The primary active ingredient in Ketanov is Ketorolac Tropetamine. Each tablet contains 10 mg of this potent nonsteroidal anti-inflammatory drug (NSAID).
Mechanism of Action
Ketorolac Tropetamine works by inhibiting the synthesis of prostaglandins, which are mediators of inflammation and pain. By blocking the action of cyclooxygenase, it reduces pain, inflammation, and fever.
Pharmacological Properties
Ketanov exhibits analgesic, anti-inflammatory, and antipyretic properties. It is rapidly absorbed after oral administration and reaches peak plasma concentrations within 1-2 hours. The drug is highly protein-bound and undergoes hepatic metabolism with a half-life of approximately 5 hours.
Indications for Use
Ketanov is indicated for the short-term management of moderate to severe acute pain. It is effective in treating pain associated with post-operative procedures, dental surgeries, musculoskeletal injuries, and other conditions requiring potent analgesia.
Contraindications
- Hypersensitivity: Patients with a known hypersensitivity to Ketorolac or any other component of the product should not use Ketanov.
- Peptic Ulcer Disease: Ketanov is contraindicated in individuals with active peptic ulcer disease, recent gastrointestinal bleeding, or perforation due to the increased risk of exacerbating these conditions.
- Renal Impairment: Ketanov should be avoided in patients with severe renal impairment or those at risk of renal failure secondary to volume depletion.
- Asthma and Allergic Reactions: Individuals with a history of asthma, urticaria, or allergic-type reactions to aspirin or other NSAIDs should not use Ketanov.
Side Effects
Common side effects of Ketanov may include gastrointestinal disturbances, such as dyspepsia, nausea, and abdominal pain. Other adverse effects may involve renal impairment, hypersensitivity reactions, and central nervous system manifestations like dizziness or headache.
Usage Instructions
For adults, the recommended dosage is one Ketanov tablet (10 mg) every 4-6 hours, not exceeding 40 mg within a 24-hour period. Dosage adjustments may be necessary based on individual pain severity and response. The tablets should be swallowed whole with a full glass of water and taken with food to minimize gastrointestinal discomfort.
Benefits Compared to Analogues
Ketanov offers rapid and potent analgesia with a favorable safety profile compared to some other NSAIDs. Its dosing regimen allows for effective pain relief in various acute conditions while minimizing the risk of adverse effects like gastrointestinal bleeding or cardiovascular events.
Suitable Patient Groups
Ketanov is suitable for adults requiring short-term management of moderate to severe pain. It is not recommended for children, elderly individuals with compromised renal function, or pregnant women due to potential risks associated with NSAID use.
Storage and Shelf Life
Ketanov tablets should be stored in a cool, dry place away from direct sunlight and moisture. The shelf life of the product is typically 2-3 years from the manufacturing date. Do not use Ketanov beyond the expiration date printed on the packaging.
Packaging Description
Ketanov tablets are typically packaged in blister packs to ensure product integrity and protection from external factors. Each pack contains 10 coated tablets, with clear labeling of the product name, strength, and dosage instructions.
