Latren solution 0.5 mg/ml. 200 ml.

Description

Latren Composition
active substance: 1 ml of solution contains 0.5 mg of pentoxifylline;

excipients: sodium chloride, potassium chloride, calcium chloride, sodium lactate solution, water for injection.

Latren Indications
Atherosclerotic encephalopathy ischemic cerebral stroke; discirculatory encephalopathy; peripheral circulatory disorders caused by atherosclerosis, diabetes mellitus (including diabetic angiopathy), inflammation; trophic disorders in tissues associated with venous damage or microcirculation disorders (post-thrombophlebitic syndrome, trophic ulcers, gangrene, frostbite); obliterating endarteritis; angioneuropathy (Raynaud’s disease); circulatory disorders of the eye (acute, subacute, chronic circulatory failure in the retina and choroid); dysfunction of the inner ear of vascular origin, accompanied by hearing loss.

Latren Contraindications
Latren® is contraindicated:

patients with hypersensitivity to pentoxifylline, to other methylxanthines or to any of the excipients of Latren®;
patients with massive bleeding (risk of increased bleeding)
patients with extensive retinal hemorrhage, with cerebral hemorrhages (risk of increased bleeding). If during treatment with pentoxifylline there is a retinal hemorrhage, the drug should be discontinued immediately;
patients in the acute period of myocardial infarction
patients with stomach ulcers and / or intestinal ulcers;
patients with hemorrhagic diathesis.

Latren Method of administration and dosage
Intravenous infusion is the most effective form of parenteral administration of the drug and is better tolerated. The dosage regimen is determined by the doctor and depends on the severity of circulatory disorders, body weight and treatment tolerance. Infusion can only be performed if the solution is clear.

The following treatment regimens recommended for adults: 1. Infusion of 100-600 mg of pentoxifylline 1-2 times a day. The duration of the intravenous infusion is 60-360 minutes, that is, the administration of 100 mg of pentoxifylline should last at least 60 minutes.

In a serious condition of the patient (especially with constant pain, with gangrene or trophic ulcers), it is possible to carry out an infusion of pentoxifylline within 24 hours. With this scheme of administration, the dose is determined at the rate of 0.6 mg / kg / h. The calculated daily dose for a patient with a body weight of 70 kg is 1000 mg, for a patient with a body weight of 80 kg – 1150 mg. Regardless of the patient’s body weight, the maximum daily dose is 1200 mg. The volume of infusion solutions is calculated individually, taking into account concomitant diseases, the patient’s condition, and averages 1-1.5 liters per day.
The duration of the parenteral course of treatment is determined by the doctor who carries out the treatment.

Children
There is no experience of using the drug in children.