Liveria IC (metadoxine) tablets 0.5 g. №20

Description

Liveria IC composition 
active substance: metadoxine;
1 tablet contains 0.5 g of methadoxin;
Excipients: microcrystalline cellulose, magnesium stearate, colloidal anhydrous silica, croscarmellose sodium.

Dosage form
Tablets.

Pharmacological properties
This drug Liveria IC is one of the drugs used to treat alcohol dependence.
The main active ingredient is metadoxin. This substance, when used appropriately, has anti-alcoholic, detoxifying and hepatoprotective properties. It is able to activate liver enzymes involved in the metabolic processes of ethanol, which helps to accelerate the process of removing ethyl alcohol and acetaldehyde from the human body, reducing their toxic effects. Increases the resistance of hepatocytes, products of fat oxidation induced by the influence of various toxins, including ethanol.
Prevents the accumulation of lipids in hepatocytes, which is the prevention of the development of fatty liver infiltration. It prevents the formation of fibronectin and collagen, which, in turn, inhibits the development of liver cirrhosis. It activates the systems of neurotransmitters, as a result of which there is an improvement in the acuity of thinking and short-term memory. Produces a prophylactic effect in case of motor excitement caused by the use of ethanol. It has a nonspecific antidepressant and anxolytic effect, reducing the craving for alcohol.
Reduces the relief of withdrawal symptoms, reducing mental and somatic manifestations of the hangover syndrome.

Indications
The specified pharmaceutical agent is used in the treatment of alcohol dependence.
In particular, it has the property:

• reduce the toxic effects of alcohol;
• fight acute alcohol intoxication (mild and moderate);
• fight alcohol withdrawal syndrome;
• chronic alcoholism.

It is also used in the complex therapy of liver diseases, especially alcoholic etiology.

Contraindications
The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or one of the auxiliary components.
It should be borne in mind that the simultaneous use of levodopa reduces its medicinal efficacy. Therefore, this drug should be used with caution in Parkinson’s disease and against the background of the therapy of this disease with levodopa.
It is important to avoid oral administration of the oral form of the drug Liveria in severe alcohol poisoning, accompanied by vomiting, loss of consciousness.

Children
Not used in pediatrics.

Application during pregnancy and lactation
The drug should not be administered during pregnancy.
If there is a need to use this drug during lactation, breastfeeding should be suspended for this period.

Method of administration and dosage
The drug Liveria IC is administered orally.
Recommended dosages:

• to reduce the toxic effects of alcohol – 2 tablets half an hour or an hour before drinking alcohol, or 1 tablet half an hour after drinking alcohol;
• in acute alcohol poisoning of mild and moderate severity 0 1 tablet 2 times a day, 1 quarter of an hour – half an hour before eating, possibly increasing the dose to 2-3 tablets per 1 dose. Treatment lasts from 3 days to 7 weeks;
• in the complex treatment of the liver and chronic alcoholism – 1 tablet twice a day for 1 quarter of an hour – half an hour before eating, but no more than 3 tablets per day. Treatment lasts at least 3 months.

Correction of dosage and duration of treatment is determined individually by the attending physician.

Overdose
Overdose has not been observed at the moment.
In case of excessive intake of the drug, symptomatic treatment is recommended, taking sorbents.

Side effects
When treating with this drug, side effects may occur in case of manifestation of individual intolerance. In particular:

• nausea, constipation, diarrhea, vomiting, dyspepsia;
• itching, allergic urticaria;
• other manifestations of allergic reactions.

Storage conditions and periods
Expiration date – no more than 3 years from the date of issue indicated on the packaging by the manufacturer.
Storage temperature should not exceed 25 ° C.