Description

Meralis (xylometazoline hydrochloride) Nasal Spray 0.05% 10 ml

Ingredients

Active ingredient: Xylometazoline hydrochloride 0.05% w/v. Inactive ingredients include benzalkonium chloride, sodium dihydrogen phosphate dihydrate, disodium phosphate dodecahydrate, and purified water.

Dosage

Adults and children over 12 years: 1-2 sprays into each nostril every 10-12 hours. Do not exceed 2 applications in 24 hours.

Indications

Meralis Nasal Spray is indicated for the relief of nasal congestion associated with hay fever, sinusitis, and other upper respiratory allergies.

Contraindications

Do not use Meralis Nasal Spray if you are allergic to xylometazoline or any other ingredients in the product. Consult a healthcare professional before use if you have heart disease, high blood pressure, thyroid problems, diabetes, or prostate issues.

Directions

1. Clear nasal passages before use.
2. Shake the bottle gently before each use.
3. Administer the spray as directed.
4. Avoid exceeding the recommended dosage.

Scientific Evidence

Xylometazoline hydrochloride, the active ingredient in Meralis Nasal Spray, is a sympathomimetic compound that works by constricting blood vessels in the nasal passages. This action leads to a decrease in swelling and congestion, allowing for easier breathing. Studies have shown the efficacy of xylometazoline in providing rapid relief from nasal congestion with minimal systemic absorption, making it a preferred choice for nasal decongestion.

Additional Information

It is important to use Meralis Nasal Spray as directed and not exceed the recommended dosage to avoid adverse effects. Prolonged use of nasal decongestants like xylometazoline can lead to rebound congestion, where the nasal passages become more congested when the medication is stopped. If symptoms persist after the recommended duration of use, consult a healthcare professional for further evaluation.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the effectiveness of xylometazoline hydrochloride in providing rapid and long-lasting relief from nasal congestion compared to placebo. Additionally, comparative studies have shown that xylometazoline nasal spray is equally effective or superior to other nasal decongestants in improving nasal airflow and reducing congestion symptoms. This highlights the efficacy and competitive edge of Meralis Nasal Spray in the management of nasal congestion.