Description

Mesacol (mesalazine) Coated Enteric Tablets 400 mg. №50

Ingredients

Active ingredient: Mesalazine 400 mg.
Other ingredients: colloidal anhydrous silica, magnesium stearate, povidone, hypromellose, methacrylic acid copolymer, talc, triethyl citrate, titanium dioxide, and yellow iron oxide.

Dosage

Recommended dosage: The usual dose is 2 to 4 tablets daily, taken in divided doses. Consult a healthcare professional for personalized dosing instructions.

Indications

Mesacol tablets are indicated for the treatment of mild to moderate ulcerative colitis and maintenance of remission.

Contraindications

Do not use Mesacol tablets if you are allergic to mesalazine or any other ingredients in the formulation. Consult your doctor before use if you have a history of kidney or liver disease.

Directions

Take Mesacol tablets with food and swallow them whole with a glass of water. Do not crush or chew the tablets.

Scientific Evidence

Mesalazine, the active ingredient in Mesacol tablets, is a 5-aminosalicylic acid (5-ASA) derivative with anti-inflammatory properties. It acts topically on the colonic mucosa, reducing inflammation and symptoms associated with ulcerative colitis. Clinical studies have demonstrated the efficacy of mesalazine in inducing and maintaining remission in patients with ulcerative colitis.

Additional Information

Mesacol tablets have a special enteric coating that allows the active ingredient to be released in the intestines, where it is most effective. It is important to follow the prescribed dosage and schedule to achieve optimal therapeutic outcomes.

Research studies have shown that mesalazine therapy is well-tolerated and effective in reducing the symptoms of ulcerative colitis, such as abdominal pain, diarrhea, and rectal bleeding. Long-term use of mesalazine has been associated with a lower risk of disease relapse and complications.

Comparative studies have indicated that mesalazine is as effective as sulfasalazine but with a lower risk of adverse effects, making it a preferred choice for long-term treatment of ulcerative colitis. Mesacol tablets offer a convenient and reliable option for patients requiring maintenance therapy.