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The injectable form of Mexiprim is used for the treatment of acute disorders of cerebral circulation, neurocirculatory dystonia, cognitive disorders that are triggered by the progression of atherosclerosis. In addition, it is used for the treatment of alcohol withdrawal syndrome, discirculatory encephalopathy, intoxication with antipsychotic drugs, acute inflammatory and purulent diseases of the abdominal cavity and anxiety conditions caused by neurological disorders.
Description
Mexiprim composition
active substance: 1 ml of the drug contains ethylmethylhydroxypyridine succinate 50 mg;
Excipient: water for injections.
Dosage form
Solution for injection.
Pharmacological properties
Mexiprim is an inhibitor of free radical processes, a membrane protector, has antihypoxic, stress, nootropic, anticonvulsant and anxiolytic effects. The drug increases the body’s resistance to various damaging factors, to oxygen-dependent pathological conditions, shock, hypoxia and ischemia, cerebrovascular disorders, alcohol intoxication and antipsychotics (neuroleptics).
Indications The injectable form of Mexiprim is used for the treatment of acute disorders of cerebral circulation, neurocirculatory dystonia, cognitive disorders that are triggered by the progression of atherosclerosis. In addition, it is used for the treatment of alcohol withdrawal syndrome, discirculatory encephalopathy, intoxication with antipsychotic drugs, acute inflammatory and purulent diseases of the abdominal cavity and anxiety conditions caused by neurological disorders.
Contraindications
Mexiprim is not used in pediatric practice if the patient has severe disorders of the liver and kidneys, hypersensitivity to the components of the drug. The drug is not used for the treatment of pregnant and lactating women.
Children
Strictly controlled clinical trials of the safety of the drug in children have not been performed, so it should not be used in this category of patients.
Application during pregnancy and lactation
The drug is not prescribed for the treatment of pregnant and lactating women, since there is insufficient data on the degree of its influence on the development of the fetus and newborn.
Method of administration and dosage
Mexiprim is administered intravenously or intramuscularly. When prescribing the drug, the doctor selects the dose individually based on the severity of the disease. For intravenous administration of the drug, it is recommended to dilute it in physiological sodium chloride solution. The starting dose of the drug can range from 50 to 100 mg three times a day. In the future, if necessary, the dose can be increased to obtain the desired therapeutic effect. If the drug is administered intravenously, the injection should last from 5 to 7 minutes. With drip administration, the solution should enter the patient’s body at a rate of 40 or 60 drops per minute. The daily dose of Mexiprim should not exceed 800 mg.
Overdose
If during the treatment with the drug the dose was accidentally or specially increased, then the patient may experience increased drowsiness, fatigue, dizziness and headaches. If there are no violations in the work of vital organs, then you can limit yourself to gastric lavage, the appointment of enterosorbents and forced diuresis.
Side effects
The drug is well tolerated by patients, however, in some cases, its intake may be accompanied by impaired coordination of movements, nausea, drowsiness, dry mouth, insomnia, increased anxiety, headaches, lability of blood pressure, emotional reactivity and the appearance of various allergic reactions.
Storage conditions and periods
Store in a dry, dark place. The shelf life of the solution for injection is 3 years.
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