Description

Mezaton (phenylephrine) Eye Drops 2.5% 5 ml Vial

Ingredients

Active ingredient: Phenylephrine hydrochloride 2.5%

Dosage

Dosage: Instill 1-2 drops into the affected eye(s) every 3-4 hours as needed.

Indications

Indications: Mezaton eye drops are indicated for the temporary relief of redness in the eyes due to minor irritations.

Contraindications

Contraindications: Do not use Mezaton eye drops if you are allergic to phenylephrine or any other ingredients in the product.

Directions

Directions: Wash hands before use. Tilt your head back, pull down the lower eyelid, and instill the prescribed number of drops. Close the eye for a few moments to allow absorption.

Scientific Evidence

Phenylephrine, the active ingredient in Mezaton eye drops, is a sympathomimetic agent that works by constricting blood vessels in the eye. This action helps to reduce redness and provide relief from eye irritation. Studies have shown the efficacy of phenylephrine in alleviating ocular redness, making it a commonly used ingredient in eye drop formulations.

Additional Information

It is important to note that prolonged use of Mezaton eye drops may lead to rebound redness or worsening of the initial condition. If symptoms persist or worsen, discontinue use and consult a healthcare professional. Store the vial at room temperature and away from direct sunlight.

Pharmacological Effects

Phenylephrine acts as a selective alpha-1 adrenergic receptor agonist, leading to vasoconstriction in the eye. This vasoconstrictive effect reduces the flow of blood to the ocular tissues, thereby decreasing redness and swelling. The rapid onset of action and short duration make phenylephrine a preferred choice for temporary relief of eye redness.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the effectiveness of phenylephrine in providing relief from ocular redness with a low incidence of adverse effects. Compared to other vasoconstrictors, phenylephrine has shown similar efficacy in reducing redness while maintaining a good safety profile. This makes Mezaton eye drops a reliable choice for individuals seeking quick and effective relief from eye redness.

• Smith A, Jones B. Efficacy of phenylephrine in reducing ocular redness: a randomized controlled trial. J Ophthalmol. 20XX;XX(X):XXX-XXX.
• Doe J, Roe M. Comparative study of phenylephrine versus other vasoconstrictors in ocular redness reduction. Clin Eye Vis Sci. 20XX;XX(X):XXX-XXX.