Micomax (fluconazole) capsules 150 mg. №3

Description

Micomax composition
active substance: fluconazole;
1 capsule contains fluconazole 150 mg;
Excipients: lactose monohydrate, pregelatinized starch, colloidal anhydrous silica, magnesium stearate, sodium lauryl sulfate, gelatin, titanium dioxide (E 171), patented blue V (E 131).

Dosage form
Capsules.

Pharmacological properties
Micomax is an antimicrobial drug intended for use in dermatological and gynecological practice in the treatment of mycoses.
Fluconazole, in particular, is capable of actively affecting the bacteria Cryptococci and various fungi of the genus “Candida” (except for the species “Candida crush”). It has the property of selectively affecting cytochrome P-450.
It has the property of converting lanosterol of mycotic cells, converting them into ergosterol, which is a membrane lipid.
As a result, in fungal cells, the synthesis of sterols is suppressed, the integrity of the cell membrane is disrupted and the fungal cell dies.
Thus, fluconazole has an effective fungistatic effect, active against opportunistic mycotic microorganisms.
Not effective against fungi of the genus “Aspergillus”.
Does not produce antiandrogenic effect.

Indications
This Micomax drug is prescribed for the treatment of sexually transmitted infections caused by microorganisms that are sensitive to the substances listed above.
In particular, for treatment:

• candidal infections of the mucous membranes;
• systemic candidiasis;
• vaginal candidiasis;
• candidal balanitis;
• other types of mycoses.

Contraindications
This drug is not used if the patient is allergic to one of its constituent drugs, including auxiliary drugs.
Also contraindicated in people with lactose intolerance.

Children
However, in general, it is undesirable to use this drug in pediatrics. Children between the ages of 12 and 17 can take the adult dosage if needed.

Application during pregnancy and lactation
This drug is contraindicated for the treatment of pregnant women (only if absolutely necessary).
Lactation is suspended for the duration of treatment with this drug.

Method of administration and dosage
Micomax is taken 150 mg, once a day, once.
If necessary, taking the drug can be repeated.
Elderly patients, as well as patients with renal impairment, should not change the dosage.
Caution should be exercised when treating patients with hepatic insufficiency, since in medical practice there are not enough observations when treating this group of patients.

Overdose
Overdose with this drug has not been recorded at the moment.
Fluconazole overdose can cause:

• hallucinations;
• paranoid delusions.

Symptomatic treatment is recommended, aimed at the speedy elimination of drug residues from the body – gastric lavage, intake of sorbents, active diuresis, hemodialysis.
In particular, hemodialysis removes 50% of the fluconazole taken within 3 hours.

Side effects
The drug can occasionally cause side reactions in the form of:

• gastrointestinal disorders – nausea, vomiting, diarrhea;
• allergic reactions in the form of itching, allergic urticaria;
• hepatitis, jaundice, liver failure;
• headache, drowsiness, paresthesia;
• nephritis, acute renal failure;
• thrombocytopenia, leukopenia, neutropenia, agranulocytosis;
• seizures, anemia, flatulence, dry mouth.

Storage conditions and periods
Shelf life is 3 years, which is counted from the production date indicated on the package.
Storage temperature should not exceed 25 ° C.