Description

Monosan (Isosorbide Mononitrate) Tablets 20 mg. №30

Ingredients

Each tablet contains 20 mg of Isosorbide Mononitrate.

Dosage

The usual dose is one tablet twice daily, with a 7-hour interval between doses.

Indications

Monosan tablets are indicated for the prevention and treatment of angina pectoris.

Contraindications

Do not use Monosan if you have hypotension, severe anemia, or are allergic to nitrates.

Directions

Swallow the tablets whole with water. Do not crush or chew them.

Scientific Evidence

Studies have shown that Isosorbide Mononitrate, the active ingredient in Monosan tablets, is effective in reducing the frequency and severity of angina attacks. It works by dilating the blood vessels, improving blood flow to the heart, and reducing the workload on the heart muscle.

Additional Information

It is important to follow the prescribed dosage of Monosan tablets to achieve optimal therapeutic effects. If you experience any side effects or have concerns about the medication, consult your healthcare provider.

Pharmacological Effects

Isosorbide Mononitrate is a vasodilator that primarily acts on the veins, reducing the preload on the heart and decreasing myocardial oxygen demand. This mechanism helps in the management of angina by improving blood flow to the heart muscle and reducing the frequency of angina attacks.

Clinical Trials and Comparative Effectiveness

In a comparative study published in the Journal of the American College of Cardiology, Isosorbide Mononitrate demonstrated similar efficacy to other nitrate medications in the treatment of stable angina. The study highlighted the favorable safety profile and tolerability of Isosorbide Mononitrate compared to other nitrates.