Description

Nebival (nebivolol hydrochloride) tablets 5 mg. №80

Ingredients

Active ingredient: Nebivolol hydrochloride

Dosage

Dosage: The recommended dose is 5 mg once daily. It can be taken with or without food.

Indications

Indications: Nebival is indicated for the treatment of hypertension (high blood pressure).

Contraindications

Contraindications: Do not use Nebival if you have a history of severe bradycardia (slow heart rate), heart block, or severe hepatic impairment.

Directions

Directions: Take Nebival exactly as prescribed by your healthcare provider. Do not exceed the recommended dose.

Scientific Evidence

Nebivolol, the active ingredient in Nebival, is a highly selective beta-blocker with vasodilatory properties. Studies have shown that nebivolol effectively lowers blood pressure by reducing peripheral vascular resistance. Additionally, nebivolol has been found to improve endothelial function, making it a favorable choice for patients with hypertension and endothelial dysfunction.

Additional Information

Nebivolol’s unique mechanism of action sets it apart from other beta-blockers. It not only blocks beta receptors but also stimulates the production of nitric oxide, leading to vasodilation and improved cardiovascular function. This dual action makes nebivolol a preferred option for patients with hypertension and other cardiovascular conditions.

Research studies have demonstrated the efficacy and safety of nebivolol in the management of hypertension. A study published in the American Journal of Cardiovascular Drugs concluded that nebivolol is well-tolerated and effective in reducing blood pressure in patients with essential hypertension. Another study in the Journal of Clinical Hypertension highlighted the beneficial effects of nebivolol on endothelial function and arterial stiffness.