Description

Nimesulid-Fitofarm tablets 100 mg. №12

Ingredients

Nimesulide 100 mg per tablet, excipients.

Dosage

The recommended dosage is 100 mg once daily.

Indications

Nimesulid-Fitofarm tablets are indicated for the relief of pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, and acute musculoskeletal disorders.

Contraindications

Do not use in patients with a history of hypersensitivity to nimesulide or other NSAIDs, active peptic ulcer, severe heart failure, or renal failure.

Directions

Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence

Nimesulide is a selective COX-2 inhibitor with anti-inflammatory, analgesic, and antipyretic properties. Studies have shown that nimesulide effectively reduces pain and inflammation in various conditions. Research published in the Journal of Clinical Rheumatology demonstrated the efficacy of nimesulide in the management of osteoarthritis pain.

Additional Information

It is important to monitor renal function in patients taking nimesulide long-term. Avoid concomitant use with other NSAIDs to reduce the risk of gastrointestinal complications. Consult a healthcare professional before starting nimesulide therapy, especially in patients with a history of gastrointestinal disorders.

Nimesulid-Fitofarm tablets 100 mg. №12 provide effective relief for pain and inflammation associated with various musculoskeletal conditions. The pharmacological action of nimesulide involves inhibiting the production of prostaglandins, which are mediators of pain and inflammation in the body. This targeted mechanism of action helps to alleviate symptoms while minimizing systemic side effects.

Clinical trials have shown that nimesulide offers comparable effectiveness to other NSAIDs with a lower risk of gastrointestinal adverse effects. A study published in the European Journal of Clinical Pharmacology found nimesulide to be well-tolerated and effective in the treatment of acute pain. The favorable safety profile of nimesulide makes it a valuable option for patients requiring long-term pain management.