Description

Nimid (Nimesulide) Gel 1% 30 g Tube

Ingredients:

Active ingredient: Nimesulide 1%
Other ingredients: Carbomer, propylene glycol, isopropyl alcohol, purified water.

Dosage:

Apply a thin layer of Nimid gel to the affected area 2-3 times a day.
Do not exceed the recommended dosage.

Indications:

Nimid gel is indicated for the relief of pain and inflammation in conditions such as:
– Muscle strains
– Sprains
– Sports injuries
– Osteoarthritis

Contraindications:

Do not use Nimid gel if you:
– Are allergic to nimesulide or any other ingredients in the gel
– Have a history of asthma, urticaria, or allergic-type reactions after taking NSAIDs

Directions:

– Clean and dry the affected area before applying the gel.
– Gently massage the gel into the skin until absorbed.
– Wash hands after application.

Scientific Evidence:

Nimesulide, the active ingredient in Nimid gel, is a selective COX-2 inhibitor with anti-inflammatory, analgesic, and antipyretic properties. Studies have shown that nimesulide effectively reduces pain and inflammation in musculoskeletal conditions. Research by Marcolin et al. (2018) demonstrated the superior efficacy of nimesulide gel compared to placebo in relieving pain in patients with osteoarthritis.

Additional Information:

– Nimid gel is for external use only. Avoid contact with eyes, mucous membranes, or open wounds.
– Consult a healthcare professional before using Nimid gel if you are pregnant, breastfeeding, or have any medical conditions.

Pharmacologically, nimesulide works by inhibiting the enzyme cyclooxygenase-2 (COX-2), which plays a key role in the inflammatory process. By selectively targeting COX-2, nimesulide reduces the production of pro-inflammatory prostaglandins, thereby alleviating pain and swelling at the site of application.

In comparative studies, nimesulide gel has shown comparable efficacy to other topical NSAIDs in managing pain and inflammation associated with musculoskeletal disorders. Its favorable safety profile and localized action make it a preferred choice for patients requiring targeted pain relief.