Description
Noradrenalin Concentrate for Infusions 2 mg/ml. 8 ml. №10
Ingredients
- Each ml contains 2 mg of Noradrenalin (Norepinephrine) as the active ingredient.
Dosage
- The recommended dosage is determined by a healthcare professional based on the patient’s condition and response to treatment.
Indications
- Noradrenalin concentrate is indicated for the treatment of hypotension and shock.
- It works by constricting blood vessels and increasing blood pressure.
Contraindications
- Do not use Noradrenalin concentrate in patients with hypotension due to volume depletion.
- It is also contraindicated in patients with peripheral vascular thrombosis.
Directions
- Noradrenalin concentrate is for intravenous use only.
- It should be administered by a healthcare professional in a controlled setting.
Scientific Evidence
- Noradrenalin has been extensively studied for its efficacy in treating hypotension and shock.
- Research published in the Journal of Intensive Care Medicine demonstrated that Noradrenalin was effective in improving mean arterial pressure and reducing the need for additional vasopressors in critically ill patients.
Additional Information
- Noradrenalin concentrate should be stored at controlled room temperature.
- It is important to monitor the patient’s blood pressure closely during administration to avoid complications.
Pharmacological Effects
- Noradrenalin acts on alpha-adrenergic receptors in blood vessels, causing vasoconstriction and increasing blood pressure.
- It also stimulates beta-adrenergic receptors, leading to increased heart rate and contractility.
Clinical Trials
- In a comparative study published in Critical Care Medicine, Noradrenalin was found to be more effective than dopamine in improving blood pressure and organ perfusion in patients with septic shock.
