Novocainamid (procainamide) ampoules 10% 5 ml. №10

Description

Novocainamid composition and form of release
The active ingredient is procainomide hydrochloride (novocainmide), excipients. It is produced in tablet form, as well as in the form of a solution for injection, poured into 5 ml ampoules.

Indications
Novocainamid is used to treat cardiac arrhythmias, for example, with tachycardia, including paroxysmal, as well as with extrasystole, atrial fibrillation (paroxysmal), etc.
It is able to reduce the excitability of the heart muscle, suppress displaced sources of heart rhythm, has the properties of local anesthesia. Novocainomide belongs to the group of class IA antiarrhythmic drugs, has a membrane stabilizing effect.

Contraindications
It should not be prescribed for severe heart failure, conduction disturbances, allergies to the components of the drugs.

Application during pregnancy and lactation
It is strictly prohibited during pregnancy and lactation.

Method of administration and dosage
Novocainamid is used exclusively in stationary conditions.
For the treatment of paroxysmal tachycardia, Novocainomil is administered drip (0.2-0.5 grams), when the attack of paroxysm is removed, the introduction of 1.25 g is permissible.
Novocainamid is also prescribed as an intramuscular injection (5-10 ml, up to 4 times a day). A combination of drip and intravenous administration is possible. In this case, the drug is dissolved in glucose or sodium chloride. When administered at a rate of 50 mg per minute, pulse, electrocardiogram and pressure should be monitored. Insertion too quickly can lead to collapse, intracardiac block, and asystole (cardiac arrest). Treatment is immediate administration of norepinephrine or mezatone.
A more accurate dosage and timing of treatment is prescribed by a doctor.
The maximum permissible dosage of Novocainomide: 1 gram per dose, up to 4 grams per day. When administered intravenously, the daily dose should not exceed 3 grams of Novocainamid solution.

Overdose
Overdose symptoms are depression of the central nervous system (agitation, convulsions, pressure drop, trembling of the limbs, loss of consciousness, collapse). Perhaps the development of tachyarrhythmias, tachycardia, asystole, oliguria, ataxia, myasthenia gravis, etc. Symptomatic treatment is prescribed. there is no antidote.

Side effects
The most common side effects are a drop in blood pressure, weakness, nausea, and sleep disturbance. From the side of the central nervous system, the development of myasthenia gravis, psychosis, depression, insomnia, ataxia, and a state of weakness is possible. From the side of the cardiovascular system: pressure drop, tachycardia, tachyarrhythmia, bradycardia, collapse, asystole.
From the lymphatic and circulatory system: development of pancytopenia, leukopenia, thrombocytopenia, neutropenia, agranulocytosis, hypoplastic anemia, eosinophilia, hypergamaglobulinemia is possible. Allergic skin reactions such as urticaria, erythema, angioedema, decreased immunity, hepatitis, lupus may also occur.

Storage conditions and periods
It is able to retain its medicinal properties for up to 3 years, subject to storage conditions – out of direct sunlight and an ambient temperature not higher than + 25 ° C.