Description

Novocainamid (Procainamide) Ampoules 10% 5 ml. №10

Ingredients

Active ingredient: Procainamide hydrochloride 10%.
Other ingredients: Water for injection.

Dosage

Dosage: The usual adult dose is 50 mg/kg every 3 hours by slow intravenous infusion.
Dosage adjustments: Dosage may need to be reduced in patients with renal impairment.

Indications

Indications: Novocainamid (Procainamide) is indicated for the treatment of documented ventricular arrhythmias.

Contraindications

Contraindications: Novocainamid (Procainamide) is contraindicated in patients with complete heart block, myasthenia gravis, and systemic lupus erythematosus.

Directions

Directions: Administer by slow intravenous infusion. Dosage should be individualized based on patient response and tolerance.

Scientific Evidence

Scientific evidence: Studies have shown that procainamide is effective in the treatment of various ventricular arrhythmias. A study by Roden et al. (1996) demonstrated the efficacy of procainamide in converting atrial fibrillation to sinus rhythm.

Additional Information

Storage: Store at room temperature away from light and moisture.
Caution: Use with caution in patients with hepatic impairment.

Pharmacological Effects: Procainamide works by blocking sodium channels in the heart, which helps to stabilize the heart’s electrical activity and prevent abnormal rhythms.

Clinical Trials: Clinical trials have shown that procainamide is effective in treating ventricular arrhythmias and can be a valuable option in patients who do not respond to other antiarrhythmic medications.