Nutriflex Lipid suspension for infusions 1250 ml. №5

$687.00

This drug Nutriflex is used for parenteral nutrition for both adults and children, when oral or enteral nutrition is not possible, insufficient or contraindicated.
Recommended for patients with moderate to severe catabolism.

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Description

Nutriflex composition
Main active ingredients: glucose, soybean oil, sodium dihydrogen phosphate dihydrate, zinc acetate dihydrate, triglycerides, isoleucine, leucine, lysine hydrochloride, methionine, phenylalanine, threonine, tryptophan, valine, arginine, histidine hydrochloric acid monohydrate, gistidine hydrochloric acid monohydrate , glycine, proline, serine, sodium hydroxide, sodium chloride, sodium acetate trihydrate, potassium acetate, magnesium acetate tetrahydrate, calcium chloride dihydrate, electrolytes (sodium, potassium, magnesium, calcium, phosphate, chloride, acetate), lipids, amino acids, hydrocarbons , nitrogen.
Auxiliary components – citric acid monohydrate, egg lecithin, glycerin, sodium oleate, water for injection.

Release form
This drug is available in the form of an emulsion for infusion, in a three-chamber bag, with a volume of  1250 ml each, with a caloric value of 1475 kcal.

Pharmacological properties
This drug Nutriflex belongs to a group of drugs that are used for parenteral nutrition, which include amino acids, fats, carbohydrates, electrolytes.
It is especially recommended for patients who need an increased dose of protein, fat, glucose for energy, in particular, in the treatment and prevention of protein deficiency after surgery, injuries, burns, in ENT practice, and in other cases when enteral nutrition is impossible.
In particular, it contains glucose as an energy source for amino acid metabolism. Amino acids, in turn, play an important role in protein synthesis.
Since the composition of the drug, in addition to glucose, includes a lipid emulsion, its use reduces the risk of thrombophlebitis.
This is especially important, since the risk of its occurrence is exacerbated if the patient is shown the introduction of hypertensive solutions into the peripheral veins.

Indications
This drug Nutriflex is used for parenteral nutrition for both adults and children, when oral or enteral nutrition is not possible, insufficient or contraindicated.
Recommended for patients with moderate to severe catabolism.

Contraindications
Not applicable if the patient has hypersensitivity (allergy) to one of the components that make up the drug.
Also contraindicated for:

  • severe hyperlipidemia;
  • severe liver failure;
  • severe blood clotting disorders;
  • congenital disorders of amino acid metabolism;
  • severe renal failure in the absence of hemodialysis or hemofiltration;
  • the period of the acute phase of shock;
  • hyperglycemia, requiring the introduction of insulin in an amount of more than 6 U / h;
  • pathologically increased concentration in blood plasma of any of the electrolytes included in the preparation;
  • general contraindications to infusion therapy;
  • unstable conditions (including post-traumatic conditions, diabetes mellitus, myocardial infarction, etc.);
  • hemophagocytic syndrome.

Children
In pediatrics, it can be used after reaching 2 years of age.

Application during pregnancy and lactation
Treatment of pregnant women with this drug is contraindicated.
During treatment, lactation should be suspended.

Method of administration and dosage
The drug Nutriflex is intended exclusively for intravenous administration into the central veins.
The dosage and rate of infusion are prescribed by the doctor on an individual basis and are determined by the patient’s ability to excrete lipids and metabolize glucose.
The infusion can be continued for as long as the patient’s clinical condition requires, based on the daily requirement for glucose, lipids and amino acids.
The dose should be selected individually and when choosing the size of the bag, take into account the patient’s condition, body weight and the need for nutrients.
The maximum daily dosage is 35 ml per 1 kg of body weight.
The maximum infusion rate is 1.7 ml per 1 kg of body weight per hour.
For patients weighing 70 kg, the infusion rate is 119 ml per hour.
The daily dose for children aged 2-5 years is 25 ml per 1 kg of body weight.
The daily dose for children aged 6 to 14 years is 17.5 ml per 1 kg of body weight.
For children over 14 years of age, the drug is administered at a dosage similar to that for adults.

Overdose
Overdose can manifest itself as:

  • feelings of heat;
  • tachycardia;
  • pulmonary edema;
  • imbalance of electrolytes;
  • lipid overload.

This condition can also be observed at the recommended infusion rate in the event that the patient’s clinical condition changes dramatically and severe renal or hepatic failure develops.
Treatment: cessation of lipid infusion, symptomatic therapy.

Side effects
Most often, the drug is well tolerated. In some cases, when a hypersensitivity reaction occurs, side effects are also possible, such as:

  • allergic reactions (anaphylactic shock (rare), fever, chills, tremors, skin rash, allergic urticaria);
  • breathing changes (tachypnea);
  • arterial hypertension, arterial hypotension;
  • increased activity of liver enzymes;
  • hemolysis;
  • reticulocytosis;
  • abdominal pain, headache;
  • hyperglycemia, metabolic acidosis;
  • shortness of breath, cyanosis.

If you experience any unusual side effects as a result of taking this drug, you should consult your doctor about possible changes in the treatment regimen.

Storage conditions and periods
The shelf life of the drug Nutriflex is no more than 2 years from the production date indicated on the package.
This medicinal product should be stored in a dry place out of the reach of children, at a temperature not exceeding 25 ° C.
The introduction is carried out immediately after preparation of the solution. If the drug is not used immediately, and there is a need to introduce acceptable additives, then this solution can be stored for 4 days at a temperature of 2-8 ° C.
After mixing the contents of three chambers, the drug retains its properties for 48 hours, at a temperature not higher than 25 ° C.