Olmesar 20 (olmesartan medoxomil) coated tablets 20 mg. №28

Description

Olmesar 20 composition and form of release
Active ingredient: olmesartan medoxomil (20 mg).
Available in tablet form.

Pharmacological properties
It is a blood pressure lowering agent. It is a blocker of angiotensin II receptors. It removes all the effects of angiotensin II, which leads to an increase in renin levels, a decrease in the concentration of aldosterone in the blood.

Indications
Olmesar 20 is used for essential arterial hypertension.

Contraindications:

• if you are allergic to olmesartan;
• with intolerance to auxiliary components;
• during pregnancy or planning a pregnancy;
• with obstruction of the biliary tract;
• with the simultaneous use of drugs containing aliskiren;
• with diabetes mellitus;
• with renal failure (with a GFR of less than 60 ml / minute / 1.73 m2).

Application during pregnancy and lactation
Contraindicated.
The drug is prohibited for use in women planning pregnancy or pregnant women. When pregnancy is diagnosed, treatment is stopped immediately.
In the II and III trimesters, the drug has a toxic effect on the fetus (suppression of renal function, delayed ossification of the skull bones, oligohydramnios) and the newborn (arterial hypotension, renal failure, hyperkalemia). Breastfeeding is stopped for the duration of treatment.

Method of administration and dosage
Olmesar 20 is administered orally, without chewing, at about the same time every day, with or without food. The tablets are taken with a sufficient amount of liquid.
The standard starting dose for adults is 10 mg once a day. If there is no sufficient decrease in blood pressure, the dose is increased to 20 mg 1 time per day. If necessary, you can increase the dose to the maximum (40 mg 1 time per day) or add hydrochlorothiazide to the treatment.
The antihypertensive effect is usually observed within two weeks after the start of therapy, and the maximum effect is observed after 8 weeks.

Overdose
The most likely adverse effect of an overdose is a decrease in blood pressure.
In case of overdose, it is necessary to monitor the patient, conduct symptomatic, supportive therapy.

Side effects:

• Hematological disorders: thrombocytopenia.
• Neurological disorders: dizziness, cephalalgia (headache).
• Respiratory disorders: rhinitis, pharyngitis, bronchitis, cough.
• Digestive disorders: nausea, diarrhea, gastroenteritis, dyspepsia, abdominal pain, vomiting.
• Dermatological disorders: urticaria, pruritus, angioedema, rash, allergic dermatitis.
• Musculoskeletal disorders: back pain, arthralgia, bone pain, arthritis.
• Very rare: myalgia, muscle cramps.
• Urinary disorders: urinary tract infection, hematuria, acute renal failure.
• Changes in laboratory parameters: an increase in the level of creatinine, urea in the blood, an increase in the activity of liver enzymes, an increase in the level of creatine phosphokinase, hyperuricemia, hypertriglyceridemia, hyperkalemia.
• Cardiovascular disorders: tachycardia, excessive lowering of blood pressure, angina pectoris.
• Others: flu-like symptoms, chest pain, peripheral edema, asthenia, malaise, fatigue, drowsiness.

Storage conditions and periods
It is allowed to store for no more than two years at temperatures up to + 25 ° C.
It is forbidden to use after the expiration date indicated on the package.
Parents are obliged to ensure the safety of children, excluding the possibility of their access to medicine.