Osteopro (MCN-Saltm) tablets №30 vial

Description

Osteopro composition
1 tablet contains: active ingredient: microcrystalline hydroxyapatite complex MCNAatm (MCN-Saltm) – 1000 mg (mg) Excipients: fillers: microcrystalline cellulose, sodium carboxymethyl cellulose, hydroxypropyl cellulose; anti-caking agents: magnesium stearate, amorphous silicon dioxide. MCHAtm (MCH-Caltm) – contains 250 mg (mg) of proteins (type I collagen and non-collagen peptides, including insulin-like growth factor I and II types (IGF1 – 0.285 μg (μg), IGF2 – 0.17 μg (μg)) ), transforming growth factor beta (TGF-β – 0.0275 μg (μg)), osteocalcin – 604 μg (μg)) and 670 mg (mg) calcium hydroxyapatite (including 250 mg (mg) calcium, 125 mg ( mg) phosphorus, 4 mg (mg) magnesium, 64 μg (μg) zinc, 3.9 μg (μg) iron and 1.4 μg (μg) boron).

Properties
Osteopro contains a special compound – microcrystalline hydroxyapatite complex MCNAatm (MCN-Saltm), which is an active regulator of calcium-phosphorus metabolism. The complex has organic and mineral components. The mineral component (calcium hydroxyapatite) contains calcium, phosphorus and some other macro- and microelements (magnesium, zinc, iron, boron). Calcium is contained in the form of hydroxyapatite, which facilitates its more complete absorption from the gastrointestinal tract. Phosphorus promotes calcium fixation in bone tissue, forming hydroxyapatite (bone mineralization phase), and also reduces its excretion by the kidneys. Magnesium is involved in the regulation of bone mineralization, contributes to its flexibility, strength and improvement of reparative potential. Zinc is a cofactor of more than 300 enzymes involved in various metabolic processes, including bone tissue. Iron is involved in the metabolism of collagen, from which trabeculae of bone tissue are also built. Boron has a pronounced effect on the growth processes of bone tissue and cartilage cells, an increase in the level of osteogenesis proteins – osteocalcin, type 1 collagen, bone morphogenesis proteins 4, 6 and 7, as well as osteopontin, bone sialoprotein (BSP gene), Runx2 protein. The organic component is represented by proteins and peptides (growth factors, osteocalcin, collagen, etc.). Among the growth factors, the most important are: insulin-like growth factor 1 and 2 (IGF1, IGF2), transforming growth factor beta (TGF-β). IGF1 and IGF2 are able to influence the synthesis of collagen and other proteins in bone tissue, as well as activate the proliferation and maturation of osteoblasts. There is evidence of their influence on the formation of cartilage tissue and fracture fusion in the experiment. TGF-β has a significant effect on bone metabolism, in particular the proliferation of the cell pool and the basic substance of bone tissue. One of the key growth factors that takes an active part in all phases of the reparative process in a fracture.

Osteopro recommendations
Osteopro is an additional source of calcium, phosphorus and proteins (collagen, growth factors, osteocalcin). It is recommended to regulate calcium-phosphorus metabolism in case of calcium deficiency in the body, osteoporosis and to improve bone growth in fractures.

Mode of application
In case of fractures: from the first day of the fracture and for 14 days, it is recommended to take 1 tablet per day with a small amount of drinking water, preferably during meals. From the 15th day, it is recommended to switch to the use of 2 tablets per day (in 2 divided doses) with a small amount of drinking water, preferably during meals. The tablets can be chewed to make swallowing easier. On the recommendation of a doctor, the recommended daily dose may be increased. The course of application is determined individually. The minimum recommended course of application is 1 month. It is recommended to consult a doctor before use.
In other conditions, in order to regulate calcium-phosphorus metabolism, with a calcium deficiency in the body, osteoporosis: use for adults 2-4 tablets per day (in 2 divided doses) with a small amount of drinking water, preferably during meals. The tablets can be chewed to make swallowing easier. On the recommendation of a doctor, the recommended daily dose may be increased. The course of application is determined individually. The minimum recommended course of application is 1 month. It is recommended to consult a doctor before use.

Warning
Do not exceed the recommended daily dose. Should not be used as a substitute for a varied diet.

Contraindications
Individual sensitivity to components, hypercalcemia, hypercalciuria, urolithiasis, tissue calcification, severe renal dysfunction, hyperproliferative processes.

Shelf life
24 months from the date of production.