Description

Pregadol (pregabalin) capsules 150 mg. №30

Ingredients

Each capsule contains 150 mg of pregabalin.

Dosage

The usual dose is 150 mg per day, divided into two or three smaller doses.

Indications

Pregadol is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, and fibromyalgia.

Contraindications

Do not use Pregadol if you are allergic to pregabalin or any of the other ingredients in the capsules.

Directions

Swallow the capsules whole with water. Do not crush or chew them.

Scientific Evidence

Pregabalin, the active ingredient in Pregadol, exerts its effects by binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding reduces the release of excitatory neurotransmitters, thereby modulating pain signaling.

Several clinical trials have demonstrated the efficacy of pregabalin in the management of neuropathic pain conditions. A study by Rosenstock et al. (2004) showed that pregabalin significantly reduced pain scores and improved sleep interference in patients with diabetic neuropathy.

Additional Information

Pregadol should be used with caution in patients with a history of substance abuse due to its potential for abuse and dependence. It may also cause dizziness and drowsiness, so avoid driving or operating machinery until you know how this medication affects you.

Consult your healthcare provider before using Pregadol if you are pregnant, planning to become pregnant, or breastfeeding. Inform your doctor about all the medications you are currently taking to avoid any potential drug interactions.