Ringera lactat (sodium chloride, potassium chloride) solution for infusions 400 ml. vial

Description

Ringera lactat (sodium chloride, potassium chloride) solution for infusions 400 ml. vial

Composition

active ingredients: sodium chloride, potassium chloride, sodium lactate, calcium chloride dihydrate;

100 ml of solution contains: sodium chloride – 0.602 g; potassium chloride – 0.0373 g; sodium lactate – 0.3138 g; calcium chloride dihydrate – 0.0294 g;

ionic composition per 1000 ml of solution: Na+ – 131 mmol, K+ – 5 mmol, Ca++ – 2 mmol, Cl− – 112 mmol, lactate – 28 mmol;

excipients: water for injection.

Dosage form

Solution for infusion.

Basic physical and chemical properties: transparent colorless liquid; theoretical osmolarity – 278 mosmol / l; pH 5.5–7.5.

Pharmacotherapeutic group

Plasma substituting and perfusion solutions. Solutions for the correction of electrolyte imbalance. electrolytes.
ATX code B05B B01.

Pharmacological properties

This drug belongs to a group of pharmaceuticals – combinations of salt formulations that are recommended for use as a rehydrating agent.

The main active ingredients are sodium, calcium and potassium chloride salts.
This osmotic solution is made in full accordance with the advice that the World Health Organization recommends for use in case of intoxication and subsequent dehydration.
A saline solution is prepared from the drug in question, which is usually used in order to correct the loss of electrolytes by cells, as well as fluid, lost during diarrhea.
Due to the balanced composition, the absorption of the taken sodium and potassium salts increases, and the substances in the composition help to adjust the balance, which helps to prevent metabolic acidosis in the patient.

Indications

This drug Ringera lactat solution is used for:

• hypovolemia and extracellular dehydration due to prolonged vomiting, diarrhea, extensive burns, frostbite, peritonitis, severe infectious diseases, shock, collapse;
• during and after operations;
• metabolic acidosis;
• used to dilute concentrated electrolyte solutions.

Contraindications

The drug Ringera lactat solution in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or one of the auxiliary components.
Also contraindicated for:

• hypervolemia, heart failure, severe forms of arterial hypertension, thrombophlebitis;
• oliguria, anuria, edema, incl. brain and lungs;
• hypernatremia, hyperkalemia, hyperchloremia, hypercalcemia;
• metabolic alkalosis and severe forms of metabolic acidosis.

Application during pregnancy and lactation

This drug should not be used when treating pregnant women.
If it is necessary to take the drug during breastfeeding, lactation is suspended.

Method of administration and dosage

The drug Ringera lactat solution is intended for intravenous infusion using a dropper.
Recommended dosages (depending on age, body weight, patient’s condition, kidney function, concomitant diseases) – about 2.5 liters per day (maximum – 40 ml per 1 kg of patient weight per day).
The rate of administration is from 60 drops per minute, in special cases – jet.
The duration of treatment is limited by the need for its use, in case of fluid loss and to replace intracellular fluid loss.

Overdose

Overdose can cause hypernatremia, hypercalcemia, or hyperkalemia.
Metabolic alkalosis can also occur with impaired renal function.
An overdose manifests itself in the form of symptoms:

• weakness;
• neuromuscular arousal;
• drowsiness, confusion;
• seizures;
• coma, respiratory arrest.

In case of an overdose, the drug is discontinued. A doctor should be consulted to correct fluid and electrolyte balance.

Perhaps the use of hemodialysis, taking vitamin D.

Side effects

Usually, if the dose is not exceeded, then side effects do not occur. In some cases, side effects are possible in the form of:

• allergic reactions – itching, rash, allergic urticaria;
• phlebitis, thrombophlebitis, and other types of local reactions at the injection site;
• intestinal obstruction;
• hypervolemia, coughing, sneezing;
• panic attacks;
• imbalance of electrolytes.