Description

Rizoptan (rizatriptan) tablets 10 mg. №3

Ingredients:

Each tablet contains 10 mg of rizatriptan benzoate.

Dosage:

The recommended dosage is one tablet (10 mg) at the onset of a migraine headache. Do not exceed more than 30 mg in a 24-hour period.

Indications:

Rizoptan is indicated for the acute treatment of migraine attacks with or without aura. It helps relieve headache, pain, and other migraine symptoms.

Contraindications:

Do not use Rizoptan if you have uncontrolled hypertension, ischemic heart disease, or have used MAO inhibitors in the past 14 days. Consult a healthcare provider before use.

Directions:

Swallow the tablet whole with water. Do not crush, chew, or break the tablet. If no improvement is seen after the first dose, do not take a second dose without consulting a doctor.

Scientific Evidence:

Rizatriptan, the active ingredient in Rizoptan, is a selective 5-HT1B/1D receptor agonist known for its vasoconstrictive properties in the cranial blood vessels. Studies have shown that rizatriptan effectively reduces the severity of migraine attacks and associated symptoms compared to a placebo. Research published in the Journal of Headache and Pain demonstrated the efficacy of rizatriptan in providing rapid relief from migraine pain within 2 hours of administration.

Additional Information:

Rizoptan is a fast-acting medication that can help improve the quality of life for individuals suffering from migraines. It is important to follow the prescribed dosage and not exceed the recommended limits to avoid potential adverse effects. If you experience any serious side effects or have concerns about using Rizoptan, seek medical advice promptly.

Pharmacologically, rizatriptan works by binding to serotonin receptors in the brain, leading to vasoconstriction and inhibition of pro-inflammatory neuropeptide release. This action helps reduce the swelling of blood vessels in the brain, which is believed to be a key factor in migraine headaches.

Clinical trials have shown that Rizoptan provides effective relief for acute migraine attacks, with a significant number of patients experiencing relief from pain and associated symptoms within a short period. Compared to other triptans, rizatriptan has demonstrated similar efficacy but with a faster onset of action, making it a preferred choice for many migraine sufferers.