Description

Rizoptan (Rizatriptan) Tablets 10 mg. №3

Ingredients:

• Each tablet contains 10 mg of rizatriptan benzoate.

Dosage:

• The recommended dosage is one tablet (10 mg) at the onset of a migraine headache.
• Do not exceed more than 30 mg in a 24-hour period.

Indications:

• Rizoptan is indicated for the acute treatment of migraine attacks with or without aura.
• It helps relieve headache, pain, and other migraine symptoms.

Contraindications:

• Do not use Rizoptan if you have uncontrolled hypertension, ischemic heart disease, or have used MAO inhibitors in the past 14 days.

Directions:

• Swallow the tablet whole with water.
• Do not crush, chew, or break the tablet.
• If no improvement is seen after the first dose, do not take a second dose without consulting a doctor.

Scientific Evidence:

Rizatriptan, the active ingredient in Rizoptan, is a selective 5-HT1B/1D receptor agonist known for its vasoconstrictive properties in the cranial blood vessels. Studies have shown that rizatriptan effectively reduces the severity of migraine attacks and associated symptoms compared to a placebo. Research published in the Journal of Headache and Pain demonstrated the efficacy of rizatriptan in providing rapid relief from migraine pain within 2 hours of administration.

Additional Information:

• Rizoptan is a fast-acting medication that can help improve the quality of life for individuals suffering from migraines.
• It is important to follow the prescribed dosage and not exceed the recommended limits to avoid potential adverse effects.
• If you experience any serious side effects or have concerns about using Rizoptan, seek medical advice promptly.

Pharmacological Properties:

Rizatriptan works by binding to serotonin receptors in the brain, leading to vasoconstriction and inhibition of pro-inflammatory neuropeptide release. This action helps reduce the swelling of blood vessels in the brain, which is believed to be a key factor in migraine headaches.

Comparison to Alternatives:

Clinical trials have shown that Rizoptan provides effective relief for acute migraine attacks, with a significant number of patients experiencing relief from pain and associated symptoms within a short period. Compared to other triptans, rizatriptan has demonstrated similar efficacy but with a faster onset of action, making it a preferred choice for many migraine sufferers.