Description

Rotalfen (dexketoprofen) solution for injections 50 mg/2 ml. 2 ml. ampoules №5

Ingredients:

Each 2 ml ampoule contains 50 mg of dexketoprofen trometamol as the active ingredient. Other ingredients include water for injections, sodium hydroxide, and hydrochloric acid.

Dosage:

The recommended dosage is 50 mg (1 ampoule) administered via intramuscular injection every 8 hours as needed. Dosage adjustments may be necessary based on individual response and tolerability.

Indications:

Rotalfen is indicated for the management of moderate to severe acute pain. It is particularly useful in situations where oral administration is not feasible or when a rapid onset of action is required.

Contraindications:

Do not use Rotalfen in patients with a history of hypersensitivity to dexketoprofen or other NSAIDs. It is contraindicated in patients with active peptic ulcers, severe heart failure, and renal impairment.

Directions:

Administer Rotalfen by deep intramuscular injection into the gluteal region. The injection site should be alternated with each dose to prevent irritation.

Scientific Evidence:

Dexketoprofen, the active enantiomer of ketoprofen, exhibits potent analgesic and anti-inflammatory properties. It acts by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins involved in pain and inflammation.

Clinical trials have demonstrated the efficacy of dexketoprofen in providing rapid and effective pain relief in various acute pain conditions, including postoperative pain and musculoskeletal injuries.

Additional Information:

Rotalfen’s fast onset of action and strong analgesic effects make it a valuable option for the management of acute pain in clinical settings. Its intramuscular formulation ensures reliable and consistent drug delivery, making it suitable for use in emergency departments and postoperative care.

Compared to other NSAIDs, dexketoprofen has shown similar efficacy in pain relief with a potentially lower risk of gastrointestinal side effects, making it a favorable choice for patients with a history of gastric ulcers or gastritis.