Sinarta (glucosamine sulfate) powder for oral solution 1.5 g/3.95 g. sachet №30

Description

Sinarta (glucosamine sulfate) powder for oral solution 1.5 g/3.95 g. sachet №30

Composition

active ingredient: glucosamine sulfate;

1 sachet contains sodium salt glucosamine sulfate in terms of 100% substance – 1.884 g, in terms of glucosamine sulfate – 1.5 g;

excipients: aspartame (E 951), sorbitol (E 420), anhydrous citric acid, polyethylene glycol (macrogol) 4000.

Dosage form

Powder for oral solution.

Basic physical and chemical properties: at the time of release: odorless white or almost white crystalline powder; during the shelf life: white or almost white crystalline powder, odorless. The presence of inclusions or lumps of light brown color is allowed.

Pharmacological group

Other non-steroidal anti-inflammatory and antirheumatic drugs.
ATX code M01A X05.

Pharmacological properties

The active ingredient is the salt of the amino monosaccharide glucosamine sulfate, which is present in the human body and is used together with sulfates for the biosynthesis of hyaluronic acid in synovial fluid and glycosaminoglycans of the main substance of articular cartilage.

The mechanism of action of glucosamine sulfate is the stimulation of the synthesis of glycosaminoglycans and, accordingly, articular proteoglycans. In addition, glucosamine exhibits anti-inflammatory properties, slows down the degradation of articular cartilage mainly due to its metabolic activities, the ability to inhibit the activity of interleukin 1 (IL-1), which, on the one hand, contributes to the effect on the symptoms of osteoarthritis, and on the other hand, delays structural joint disorders, as evidenced by data from long-term clinical studies.

The effectiveness of glucosamine sulfate against osteoarthritis is evident as early as 2-3 weeks after the start of treatment.

Indications

Sinarta powder is prescribed and used to treat symptoms of osteoarthritis such as pain and functional limitation.

Contraindications

Sinarta powder drug has a number of contraindications for use: a tendency to bleeding, impaired liver and kidney function, phenylketonuria, children under 18 years of age, as well as in cases of individual intolerance to the substances that are part of this drug. Such a component in the composition of the drug as glucosamine is produced from the shell of shellfish, in this case, people who are allergic to shellfish should not use Sinatra.

Application during pregnancy and lactation

It is contraindicated to use Sinarta for women during pregnancy, as well as during breastfeeding.

Method of administration and dosage

Sinarta powder is intended for direct oral administration.
Before starting treatment, you should consult your doctor.
It is necessary to take the drug during meals, dissolving the contents of one sachet in a glass of water.
The recommended daily dose is 1 sachet (1500 mg glucosamine sulfate). The duration of therapy is 1-3 months, if there is a need, treatment can be repeated 2-3 times a year every 2 months. But it is worth noting that further use and the period of use is agreed with the doctor and is determined individually for each patient, depending on the patient’s condition and medical indications.

Overdose

There were no cases of overdose in patients taking Sinarta’s drug. In cases of intoxication, side effects may increase.

Side effects

The use of Sinarta can cause negative reactions in the form of: abdominal pain, dyspepsia, flatulence, headache, drowsiness, fatigue and dizziness. Taking the drug can also lead to the development of allergic reactions, erythema, blurred vision, as well as cause itching, angioedema, rash, urticaria, nausea, hair loss, diarrhea or constipation.