Description

Sinecod (Citrate Butamirate) Syrup 1.5 mg/ml. 100 ml Vial

Ingredients

Active ingredient: Citrate Butamirate
Other ingredients: (to be completed based on the product’s formulation)

Dosage

Adults and children over 12 years: 15 ml 3 times a day.
Children 6-12 years: 10 ml 3 times a day.
Children 2-6 years: 5 ml 3 times a day.

Indications

Sinecod syrup is indicated for the symptomatic treatment of productive cough.

Contraindications

Do not use Sinecod syrup:
– In children under 2 years of age.
– In case of hypersensitivity to the active substance or any of the excipients.

Directions

– Shake well before use.
– Use the measuring cup provided to ensure accurate dosage.
– Can be taken with or without food.

Scientific Evidence

Citrate Butamirate has been shown in studies to effectively reduce the frequency and intensity of coughing episodes by acting on the cough center in the brain. Research published in the Journal of Pulmonary Pharmacology and Therapeutics demonstrated the efficacy of citrate butamirate in managing cough symptoms in patients with acute respiratory infections.

Additional Information

Pharmacological Effects:
Citrate butamirate, the active ingredient in Sinecod syrup, exerts its antitussive action by modulating the sensitivity of the cough reflex without affecting the expectoration of mucus. This mechanism helps in reducing the urge to cough, providing relief to individuals suffering from productive cough.

Clinical Trials:
Clinical trials have demonstrated the superior efficacy of Sinecod syrup compared to a placebo in managing cough symptoms. A randomized controlled trial published in the European Respiratory Journal showed that patients receiving citrate butamirate experienced a significant reduction in cough frequency and severity compared to the control group.

In conclusion, Sinecod syrup containing citrate butamirate is a well-established antitussive medication supported by scientific evidence and clinical trials, making it a reliable choice for the symptomatic treatment of productive cough.