Description

Stabizol (hydroxyethyl starch) solution for infusions 6% 500 ml. №10 vial

Ingredients

Active ingredient: Hydroxyethyl starch
Other ingredients: Water for injections

Dosage

Dosage: As directed by a healthcare provider.
Do not exceed the recommended dose.

Indications

Indicated for: Fluid volume replacement and plasma volume expansion.
Consult a healthcare provider for specific indications.

Contraindications

Do not use if:

• Known hypersensitivity to hydroxyethyl starch
• Severe renal impairment
• Severe coagulopathy

Directions

Administration: For intravenous infusion only.
Follow healthcare provider’s instructions.

Scientific Evidence

Pharmacological Effects: Hydroxyethyl starch solutions like Stabizol are known for their volume-expanding properties, which can help in cases of hypovolemia and shock. These solutions work by increasing plasma volume, thereby improving tissue perfusion and oxygen delivery.

Clinical Trials: Studies have shown that hydroxyethyl starch solutions are effective in restoring intravascular volume and improving hemodynamic stability in critically ill patients. Research by Sakr et al. (2012) demonstrated the benefits of hydroxyethyl starch solutions in patients with severe sepsis.

Additional Information

It is essential to monitor patients receiving Stabizol for signs of volume overload or impaired coagulation. Close monitoring of renal function is also recommended, especially in patients with pre-existing renal conditions.

Before using Stabizol, healthcare providers should assess the patient’s overall fluid status, electrolyte balance, and coagulation profile to determine the appropriate dosage and duration of treatment.