Description

Sulcef (sulbactam, cefoperazone) powder for solution for injections 1 g/1 g. №1 vial

Ingredients

Active ingredients: Sulbactam and Cefoperazone.

Dosage

Dosage: The usual adult dosage is 1 to 2 g every 12 hours by intravenous injection.

Indications

Indications: Sulcef is indicated for the treatment of infections caused by susceptible strains of bacteria.

Contraindications

Contraindications: Do not use Sulcef if you are allergic to any of the ingredients or if you have a history of severe allergic reactions to beta-lactam antibiotics.

Directions

Administration: Administer by intravenous injection over 3 to 5 minutes.

Scientific Evidence

Pharmacological Effects: Sulcef combines the beta-lactamase inhibitor sulbactam with the third-generation cephalosporin cefoperazone to broaden the spectrum of antibacterial activity. This combination helps in overcoming bacterial resistance mechanisms, making it effective against a wide range of pathogens.

Clinical Trials: Clinical studies have demonstrated the efficacy of Sulcef in treating various infections, including respiratory tract infections, urinary tract infections, and skin and soft tissue infections. The dual mechanism of action of sulbactam and cefoperazone has shown promising results in combating multidrug-resistant bacteria.