Teraflex (D-glucosamine, chondroitin) capsules №120 vial

Description

Teraflex (D-glucosamine, chondroitin) capsules №120 vial

Composition

active substances: D-glucosamine hydrochloride and sodium chondroitin sulfate;

1 capsule contains 500 mg of D-glucosamine hydrochloride, 400 mg of sodium chondroitin sulfate;

Excipients: gelatin, stearic acid, magnesium stearate, manganese sulfate monohydrate.

Dosage form

Capsules.

Main physical and chemical properties: hard, transparent gelatin capsules containing powder from whitish to light beige color with crystalline particles.

Pharmacotherapeutic group

Means used in pathology of the musculoskeletal system.
ATX code M09A X.

Pharmacological properties

This drug stimulates the regeneration of cartilage tissue. Chondroitin and glucosamine are effective in osteoarthritis. The drug has an anti-inflammatory effect at the cellular level, stimulates the synthesis of both endogenous proteoglycans and endogenous hyaluronic acid, reduces the catabolic activity of chondrocytes by inhibiting certain cartilage-destroying enzymes such as collagenase, elastase, proteoglyconase, proteoglycinase and proteoglycinase , and inhibits the formation of other substances that can damage cartilage (in vitro), such as superoxide radicals; activity of lysosomal enzymes.

• Chondroitin is one of the main elements of cartilage. It reduces the activity of the inflammatory process in the early stages and thus slows down the degeneration of cartilage tissue. Helps reduce pain, improve joint function and reduce the need for nonsteroidal anti-inflammatory drugs for osteoarthritis of the knee and hip joints.
• Glucosamine is physiologically present in the human body and has chondroprotective properties. In vitro and in vivo studies have shown that glucosamine hydrochloride stimulates the synthesis of physiological glycosaminoglycans and proteoglycans by chondrocytes and the synthesis of hyaluronic acid by synoviocytes.

Indications

Teraflex capsules is used in the complex therapy of diseases of the musculoskeletal system, characterized by degenerative-dystrophic changes in the articular tissue, which allows it to be used to treat:

• primary and secondary osteoarthritis;
• osteochondrosis of the spine;
• degenerative-dystrophic changes in the joints and spine;
• traumatic damage to bones (the drug stimulates regenerative processes and accelerates the formation of callus).

Contraindications

Teraflex capsules is not prescribed if the patient has:

• severe renal failure;
• hypersensitivity to glucosamine hydrochloride or sodium chondroitin sulfate;
• pregnancy or lactation;
• age under 15.

Special care should be taken when prescribing Teraflex if the patient has a tendency to bleeding, diabetes mellitus or bronchial asthma.

Application during pregnancy and lactation

Due to the fact that clinical studies of the effect of Teraflex on the development of the fetus and newborn are absent, it is not used to treat this category of patients. If it is necessary to prescribe a remedy at the lactation stage, it is recommended to consider the question of stopping feeding.

Method of administration and dosage

Teraflex capsules are intended for oral administration. The drug is consumed regardless of food intake. Adults and children who have turned 15 years old for the first 3 weeks of treatment should take 1 capsule 3 times a day. In the future, the drug is recommended to take 1 capsule 2 times a day.
If there are no other recommendations, then the course of drug treatment can be from 3 to 6 months. If necessary, the duration of treatment can be changed taking into account the severity of the disease.

Overdose

At the moment, there have been no officially registered cases of overdose during treatment with Teraflex. However, it is reliably known that when taking chondroitin sulfate in high doses, the patient may develop nausea, vomiting and hemorrhagic rashes.
If a patient develops symptoms of drug intoxication, he is prescribed gastric lavage and symptomatic treatment.

Side effects

As a rule, patients tolerate Teraflex well. However, in some patients, its use may be accompanied by the development of abdominal pain, flatulence, stool disorders, constipation, headaches, peripheral edema, sleep disturbances, dizziness and various allergic reactions.