Tribestan (anchor creeping herb) coated tablets 250 mg. №60

Description

Tribestan (anchor creeping herb) coated tablets 250 mg. №60

Composition

active substance: anchor creeping herb dry extract (35-45: 1);

1 tablet, coated, contains anchors of creeping herb dry extract (Tribulus terrestris herba extractum siccum), (35-45: 1), (extractant: methanol 80%) – 250 mg, corresponding to furostanol saponins in terms of protodioscin – 112, 5 mg;

Excipients: microcrystalline cellulose, colloidal anhydrous silica, povidone, crospovidone, magnesium stearate, talc;

film coating: Opadray AMV 80W26601 brown (partially hydrolyzed polyvinyl alcohol, talc, titanium dioxide (E 171), iron oxide red (E 172), iron oxide black (E 172), lecithin, xanthan gum, iron oxide 17) ).

Dosage form

Coated tablets.

Main physical and chemical properties: round biconvex tablets, coated, brown with a specific odor.

Pharmacotherapeutic group

Means used in urology.
ATX code G04B X.

Pharmacological properties

Preparation of natural origin, obtained by the original technology from the terrestrial part of the plant Tribulus Terrestris L. The drug contains mainly steroidal saponins of the furostanol type, among which protodioscin predominates. The mechanism of action of the drug is due to this component.

Protodioscin is metabolized in the body to dehydroepiandrosterone (DHEA), which has a beneficial effect on cell membrane permeability, erectile function, cholesterol metabolism and immunity. Other active furostanol saponins in Tribulus Terrestris L. are likely to modulate the protodioscin effect.

Tribestan has a tonic effect and stimulates some functions of the reproductive system. In men, restores and improves libido and erection. Has a stimulating effect on spermatogenesis, increasing the number of sperm and their motility, increases testosterone levels. In women, Tribestan also improves libido, stimulates ovulation. Favorably affects the vasomotor manifestations of natural and post-castration menopausal syndrome due to its balancing effect on hormonal activity.

The results in healthy volunteers show that Tribestan affects the serum levels of pituitary-gonadal hormones, without significantly changing the levels of adrenal hormones and adrenocorticotropic hormone.

Tribestan has a hypolipidemic effect, and in patients with dyslipoproteinemia significantly reduces the level of total cholesterol and LDL (low-density lipoprotein), without a significant effect on the level of triglycerides and HDL (high-density lipoprotein) in the serum.

Tribestan has antihypertensive and diuretic effects.

Indications

Tribestan is used as a tonic agent, which increases the body’s resistance to mental and physical stress, it increases performance during long and intense sports training. Tribestan is used as a general tonic during the rehabilitation period after long and serious illnesses.
The drug is successfully used in the treatment of sexual disorders, as well as sexual dysfunctions, such as idiopathic oligoasthenoteratozoospermia, sexual weakness, azoospermia with immunological infertility.
In addition, Tribestan is prescribed to increase libido and erection in men, as well as in climacteric syndrome, frigidity and hormonal infertility in women.

Contraindications

Tribestan is not prescribed if the patient has an intolerance to the active and auxiliary components of the drug, severe cardiovascular diseases, impaired renal function and adenoma of the prostate gland.

Application during pregnancy and lactation

Tribestane is not used in the treatment of pregnant and lactating women.

Method of administration and dosage

Tribestan is intended for oral administration. The drug is taken only after meals.
With reduced libido, infertility and impotence, Tribestan should be taken one or two tablets three times a day. The duration of treatment in this case should be at least 90 days. Repetition of treatment courses is carried out until a positive therapeutic effect is obtained.
In the treatment of female endocrinological infertility, the drug is recommended to take one or two tablets three times a day. The drug is taken from the first to the twelfth day of the menstrual cycle. It is recommended to repeat the treatment monthly until pregnancy.
In the treatment of dyslipoproteinemia, patients are prescribed two tablets three times a day. The minimum course of treatment is three months.
In the treatment of menopausal and post-castration syndrome in women, the drug is recommended to be taken one or two tablets three times a day for 60 to 90 days. If there is a positive trend in the patient’s treatment, then they switch to a maintenance dosage – two tablets per day for one or two years.

Overdose

Overdose cases of Tribestan are not officially registered.

Side effects

In rare cases, taking Tribestan may be accompanied by the appearance of allergic reactions and severe nausea. When these symptoms appear, the drug should be discontinued for several days or the daily dosage should be reduced.
If you experience any unusual side effects during treatment with Tribestan, you should immediately inform your doctor about them.